Approaches to the synthesis of ureapeptoid peptidomimetics

被引：74

作者：

Kruijtzer, JAW ^{[1
]}

Lefeber, DJ ^{[1
]}

Liskamp, RMJ ^{[1
]}

机构：

[1] UNIV UTRECHT,UTRECHT INST PHARMACEUT SCI,DEPT MED CHEM,NL-3508 TB UTRECHT,NETHERLANDS

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 30期

关键词：

D O I：

10.1016/S0040-4039(97)01166-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

ureapeptoid peptidomimetics can be composed from Boc-protected N-substituted ethylenediamines. The best approach is to synthesize these from chloroacetonitrile followed by conversion to the corresponding crystalline p-nitrophenyl carbamates in order to prepare the ureapeptoids. (C) 1997 Elsevier Science Ltd.

引用

页码：5335 / 5338

页数：4

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