The Technique of Thyroid Cartilage Scaffold Support Formation for Extrusion-Based Bioprinting

被引：11

作者：

Arguchinskaya, N., V ^{[1
]}

Beketov, E. E. ^{[1
]}

Kisel, A. A. ^{[1
]}

Isaeva, E., V ^{[1
]}

Osidak, E. O. ^{[2
]}

Domogatsky, S. P. ^{[2
,3
]}

Mikhailovsky, N., V ^{[1
]}

Sevryukov, F. E. ^{[1
]}

Silantyeva, N. K. ^{[1
]}

Agababyan, T. A. ^{[1
]}

Ivanov, S. A. ^{[1
]}

Shegay, P., V ^{[4
]}

Kaprin, A. D. ^{[4
]}

机构：

[1] Minist Hlth Russian Federat, A Tsyb MRRC Branch, Natl Med Res Radiol Ctr, Obninsk, Russia

[2] Imtek Ltd, Moscow, Russia

[3] Minist Hlth Russian Federat, Russian Cardiol Res & Prod Ctr, Fed State Budgetary Inst, Moscow, Russia

[4] Minist Hlth Russian Federat, Natl Med Res Radiol Ctr, Obninsk, Russia

来源：

INTERNATIONAL JOURNAL OF BIOPRINTING | 2021年 / 7卷 / 02期

关键词：

Computer-aided design/Computer-aided manufacturing; 3D-bioprinting; Cartilage; Collagen; Gelatin; TISSUE-ENGINEERED TRACHEA; VASCULAR CHANNELS; COLLAGEN; FABRICATION; CONSTRUCTS; NETWORKS; CULTURE; HYBRID; BIOINK;

D O I：

10.18063/ijb.v7i2.348

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

During biofabrication, a tissue scaffold may require temporary support. The aim of this study was to develop an approach of human thyroid cartilage scaffold temporal support formation. The scaffold 3D-model was based on DICOM images. XY plane projections were used to form scaffold supporting part. To verify the technique, collagen hydrogel was chosen as the main scaffold component. Gelatin was applied for the supporting part. To test the applicability of the approach, a model of thyroid cartilage scaffold with the support was printed. The scaffold corresponded to a given model, although some discrepancy in geometry was observed during verification by computed tomography.

引用

页码：104 / 113

页数：10

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