Predicting Response of ADHD Symptoms to Methylphenidate Treatment Based on Comorbid Anxiety

被引：14
作者：
Blouin, Brittany [1 ]
Maddeaux, Cindy [2 ]
Firestone, Jill Stanley [2 ]
van Stralen, Judy [3 ,4 ,5 ]
机构：
[1] Univ Guelph, Guelph, ON N1G 2W1, Canada
[2] Ottawa Ctr Cognit Therapy, Ottawa, ON, Canada
[3] Queensway Carleton Hosp, Ottawa, ON, Canada
[4] Childrens Hosp Eastern Ontario, Ottawa, ON, Canada
[5] Child & Youth Wellness Ctr, Brockville, ON, Canada
来源：
JOURNAL OF ATTENTION DISORDERS | 2010年 / 13卷 / 04期
关键词：
ADHD; behavioral response; cognitive response; comorbid anxiety; methylphenidate; ATTENTION-DEFICIT HYPERACTIVITY; DEFICIT/HYPERACTIVITY DISORDER; MULTIMODAL-TREATMENT; CHILDREN; PHARMACOTHERAPY; BEHAVIOR; TRIAL; MTA;
D O I：
10.1177/1087054708326269
中图分类号：
B844 [发展心理学（人类心理学）];
学科分类号：
040202 ;
摘要：
Objective: In this small pilot study, the association of comorbid anxiety with the treatment of ADHD is studied. Methods: Eighteen volunteers from a pediatric clinic are tested for ADHD and anxiety and assessed for behavioral and cognitive ADHD symptomology. Response to methylphenidate as treatment for ADHD symptoms is measured 2 to 3 weeks, and again 4 to 6 weeks following the diagnosis of ADHD. Results: Methylphenidate proves effective for treating ADHD symptoms (both behavioral and cognitive). Participants are categorized into two groups, those with ADHD and comorbid anxiety and those with ADHD alone. Behaviorally, no statistically significant differences are seen in response between the two groups; however; cognitively, the non-anxious group improves significantly more than the anxious group. Conclusion: Although anxiety may not affect behavioral response to stimulant medication in ADHD, it does appear to affect the medication response of more subtle symptoms of cognitive performance in ADHD patients. (J of Att. Dis. 2010; 13(4) 414-419)
引用
收藏
页码：414 / 419
页数：6
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