Silver-Catalyzed Radical Cascade Sulfonation/Cycloaddition for the Construction of Multifunctional Succimides Containing Separable Z/E-Isomers

被引：17

作者：

Gu, Yan ^{[1
]}

Dai, Lei ^{[1
]}

Zhang, Jinghang ^{[1
]}

Lu, Xinchi ^{[1
]}

Liu, Xiaoqin ^{[1
]}

Wang, Chang ^{[1
]}

Zhang, Jinpeng ^{[2
]}

Rong, Liangce ^{[1
]}

机构：

[1] Jiangsu Normal Univ, Sch Chem & Mat Sci, Jiangsu Key Lab Green Synthet Chem Funct Mat, Xuzhou 221116, Jiangsu, Peoples R China

[2] Xuzhou Med Univ, Coll Publ Hlth, Xuzhou 221006, Jiangsu, Peoples R China

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2021年 / 86卷 / 03期

基金：

中国国家自然科学基金;

关键词：

547.1 Precious Metals - 802.2 Chemical Reactions;

D O I：

10.1021/acs.joc.0c02275

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A silver-catalyzed cascade cycloaddition of aza-1,6-enynes, affording multifunctional succimide frameworks initiated by the arylsulfonyl radical addition, has been developed. This process shows mild reaction conditions, excellent structural selectivity, and broad functional group tolerance. In addition, the Z/E-isomers can be easily separated, which provides an efficient method for obtaining pure Z/E-configuration products.

引用

页码：2173 / 2183

页数：11

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