Sono-Biosynthesis and Characterization of AuNPs from Danube Delta Nymphaea alba Root Extracts and Their Biological Properties

被引：14

作者：

Cudalbeanu, Mihaela ^{[1
,2
]}

Peitinho, David ^{[3
]}

Silva, Francisco ^{[3
]}

Marques, Rosa ^{[3
,4
]}

Pinheiro, Teresa ^{[4
,5
]}

Ferreira, Ana C. ^{[6
]}

Marques, Fernanda ^{[3
,4
]}

Paulo, Antonio ^{[3
,4
]}

Soeiro, Catarina F. ^{[5
]}

Sousa, Silvia Andreia ^{[5
]}

Leitao, Jorge Humberto ^{[5
]}

Tabacaru, Aurel ^{[1
]}

Avramescu, Sorin Marius ^{[2
,7
]}

Dinica, Rodica Mihaela ^{[1
]}

Cabral Campello, Maria Paula ^{[3
,4
]}

机构：

[1] Dunarea de Jos Univ Galati, Fac Sci & Environm, Dept Chem Phys & Environm, 111 Domneasca St, Galati 800201, Romania

[2] Univ Bucharest, Res Ctr Environm Protect & Waste Management, 91-95 Splaiul Independentei, Bucharest 050095, Romania

[3] Univ Lisbon, Ctr Ciencias & Tecnol Nucl, Inst Super Tecn, Campus Tecnol & Nucl,Estr Nacl 10,Km 139-7, P-2695066 Bobadela, Portugal

[4] Univ Lisbon, Dept Engn & Ciencias Nucl DECN, Inst Super Tecn, Estr Nacl 10, P-2695066 Bobadela, Portugal

[5] Univ Lisbon, Dept Bioengn, iBB Inst Bioengn & Biosci, Inst Super Tecn, P-1049001 Lisbon, Portugal

[6] Univ Lisbon, Ctr Quim Estrutural, Inst Super Tecn, Campus Tecnol & Nucl,Estr Nacl,Estr Nacl 10, P-2695066 Bobadela, Portugal

[7] Univ Bucharest, Dept Organ Chem Biochem & Catalysis, Fac Chem, 90-92 Soseaua Panduri, Bucharest 050663, Romania

来源：

NANOMATERIALS | 2021年 / 11卷 / 06期

关键词：

gold nanoparticles; Nymphaea alba; sonochemistry; biosynthesis; antimicrobial activity; antitumor activity; antioxidant compounds; COLLOIDAL GOLD NANOPARTICLES; GREEN SYNTHESIS; AQUEOUS EXTRACT; CELLULAR UPTAKE; LEAF EXTRACT; SILVER NANOPARTICLES; ANTICANCER ACTIVITY; CITRUS-LIMON; TANNIC-ACID; SIZE;

D O I：

10.3390/nano11061562

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Root extracts from Danube Delta Nymphaea alba were used to prepare gold nanoparticles (AuNPRn) by reducing HAuCl4 at different pHs (6.4-8.4) using ultrasonic irradiation: an easy, cheap, eco-friendly and green approach. Their antibacterial and anticancer activities were evaluated against Staphylococcus aureus and Escherichia coli, and A2780 ovarian cancer cells, respectively. The AuNPRn were characterized concerning their phytoconstituents (polyphenols, flavonoids and condensed tannins) and gold content. All of the nanoparticles were negatively charged. AuNPRn exhibited a hydrodynamic size distribution ranging from 32 nm to 280 nm, with the larger nanoparticles being obtained with an Au/root extract ratio of 0.56, pH 7 and 10 min of sonication (AuNPR1), whereas the smallest were obtained with an Au/root extract ratio of 0.24, pH 7.8 and 40 min of sonication (AuNPR4). The TEM/SEM images showed that the AuNPRn had different shapes. The ATR-FTIR indicated that AuNPRn interact mainly with hydroxyl groups present in the polyphenol compounds, which also confirm their high antioxidant capacity, except for AuNPR2 obtained at pH 6.4. Among the AuNPRn, the smallest ones exhibited enhanced antimicrobial and anticancer activities.

引用

页数：22

共 104 条

[1] Green Synthesis of Gold and Silver Nanoparticles by Using Amorphophallus paeoniifolius Tuber Extract and Evaluation of Their Antibacterial Activity [J].