Clinical use of a combined-action antihypertensive medication urapidil

被引:0
作者
Gaponova, N. I. [1 ]
Abdrakhmanov, V. R. [1 ]
Plavunov, N. F. [2 ]
Filatov, A. V.
Orlov, V. S. [2 ]
Filippo, D. V. [2 ]
Tereshchenko, S. N. [1 ]
机构
[1] Moscow State Medicostomatol Univ, Moscow, Russia
[2] AS Puchkov Urgent Med Care Ctr, Moscow, Russia
来源
CARDIOVASCULAR THERAPY AND PREVENTION | 2010年 / 9卷 / 01期
关键词
Arterial hypertension; antihypertensive therapy; hypertensive crise; urapidil; ARTERY BYPASS-SURGERY; HYPERTENSIVE URGENCIES; SODIUM-NITROPRUSSIDE; EMERGENCIES; INVITRO; NITROGLYCERIN; HYPOTENSION; PROFILE;
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Currently, combined antihypertensive therapy is considered as the leading strategy in the management of patients with arterial hypertension. One of the effective combined antihypertensive medications is a hybrid agent urapidil, which chemical structure provides a combination of central antihypertensive action and peripheral vasodilatation. This review discusses the results of the clinical and experimental studies on urapidil antihypertensive effectiveness. The clinical use of the medication, as well as its good tolerability and safety, is also discussed.
引用
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页码:107 / 112
页数:6
相关论文
共 37 条
[1]   Effectiveness and safety of prehospital urapidil for hypertensive emergencies [J].
Alijotas-Reig, J ;
Bove-Farre, I ;
De Cabo-Frances, F ;
Angles-Coll, R .
AMERICAN JOURNAL OF EMERGENCY MEDICINE, 2001, 19 (02) :130-133
[2]   IS BLOCKADE OF ALPHA-1-ADRENOCEPTORS FAVORABLE IN HYPOTENSION INDUCED BY STIMULATION OF SEROTONIN-1A RECEPTORS IN CONSCIOUS DOGS [J].
BELLER, KD ;
BOER, R ;
SANDERS, KH ;
WALTER, B .
DRUGS, 1990, 40 :38-41
[3]   The serotonin syndrome [J].
Boyer, EW ;
Shannon, M .
NEW ENGLAND JOURNAL OF MEDICINE, 2005, 352 (11) :1112-1120
[4]  
CASTHELY PA, 1982, ANESTH ANALG, V61, P231
[5]   ACUTE EFFECTS OF URAPIDIL ON AIRWAY RESPONSE IN HYPERTENSIVE PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY-DISEASE [J].
CAZZOLA, M ;
SPINAZZI, A ;
SANTANGELO, G ;
STEINIJANS, VW ;
WURST, W ;
SOLLEDER, P ;
GIRBINO, G .
DRUGS, 1990, 40 :71-72
[6]   Management of patients with hypertensive urgencies and emergencies - A systematic review of the literature [J].
Cherney, D ;
Straus, S .
JOURNAL OF GENERAL INTERNAL MEDICINE, 2002, 17 (12) :937-945
[7]   CLINICAL ASPECTS OF ANTIHYPERTENSIVE THERAPY WITH URAPIDIL - COMPARISON WITH HYDROCHLOROTHIAZIDE [J].
DISTLER, A ;
HAERLIN, R ;
HILGENSTOCK, G ;
PASSFALL, J .
DRUGS, 1990, 40 :21-27
[8]  
ELAGIN RI, 2003, CONS MED, V7, P1
[9]   INFLUENCE OF URAPIDIL ON INVITRO PLATELET RESPONSE TO ADRENALINE AND OTHER AGGREGATING AGENTS [J].
EMANUELLI, G ;
ANFOSSI, G ;
LANZIO, M ;
MULARONI, E ;
CALCAMUGGI, G ;
BRUNELLO, F ;
BUSCA, GP ;
CIANI, D .
PHARMACOLOGICAL RESEARCH COMMUNICATIONS, 1988, 20 (10) :883-899
[10]   COMPARISON OF INTRAVENOUS NITROGLYCERIN AND SODIUM-NITROPRUSSIDE FOR TREATMENT OF ACUTE HYPERTENSION DEVELOPING AFTER CORONARY-ARTERY BYPASS-SURGERY [J].
FLAHERTY, JT ;
MAGEE, PA ;
GARDNER, TL ;
POTTER, A ;
MACALLISTER, NP .
CIRCULATION, 1982, 65 (06) :1072-1077