How Should We Measure the Quality of Lymphadenectomy for Gastric Cancer? Anatomical Versus Numerical Criterion

被引：6

作者：

Rausei, Stefano ^{[1
]}

Galli, Federica ^{[2
]}

Lianos, Georgios ^{[3
]}

Rosa, Fausto ^{[4
]}

Cossu, Andrea ^{[5
]}

Biondi, Alberto ^{[6
]}

Martignoni, Francesco ^{[2
]}

Cananzi, Ferdinando Carlo Maria ^{[7
]}

Fumagalli, Uberto ^{[8
]}

Alfieri, Sergio ^{[4
]}

Persiani, Roberto ^{[6
]}

Quagliuolo, Vittorio ^{[7
]}

D'Ugo, Domenico ^{[6
]}

Rosati, Riccardo ^{[5
]}

机构：

[1] ASST Valle Olona, Dept Surg, Gallarate, VA, Italy

[2] Univ Insubria, Dept Surg, Varese, Italy

[3] Univ Hosp Ioannina, Dept Surg, Ioannina, Greece

[4] Catholic Univ, Div Digest Surg, Dept Surg Sci, Rome, Italy

[5] Univ Vita Salute San Raffaele, Dept Surg, Milan, Italy

[6] Catholic Univ, Div Gen Surg, Dept Surg Sci, Rome, Italy

[7] Humanitas Clin & Res Ctr, Div Surg Oncol, Rozzano, MI, Italy

[8] Brescia Univ, Dept Surg, Brescia, Italy

来源：

JOURNAL OF GASTROINTESTINAL CANCER | 2020年 / 51卷 / 03期

关键词：

Locally advanced gastric cancer; Lymphadenectomy; Number of removed lymph nodes; Cancer-related survival; SURVIVAL; SURGERY; EXTENT; CLASSIFICATION; GASTRECTOMY; DISSECTION; MORBIDITY; RESECTION; NUMBER; IMPACT;

D O I：

10.1007/s12029-019-00321-x

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

AimTo compare anatomical with numerical criterion to measure the quality of lymphadenectomy for gastric cancer.Patients and MethodsWe analyzed 447 gastric cancer patients with resectable tumor stage (R0 resection) with at least 16 examined lymph nodes.ResultsOf 447 patients, 82.6% underwent D2 lymphadenectomy for a median of total examined lymph nodes of 28. The 7-year disease-specific survival rate for the whole sample was 71.4%. Survival was significantly different between patients treated with D2 and D1 lymphadenectomy (77.4% versus 44.3%; p < 0.001) and between patients with total examined lymph nodes >= 28 and < 28 (74.5% versus 62.3%; p = 0.041). Anatomical criterion significantly differentiated 7-year survival in patients stratified according to a numerical parameter.ConclusionWe should still consider the anatomical criterion as the best item to measure the quality of lymphadenectomy for gastric cancer.

引用

页码：887 / 892

页数：6