Progressive anemia following combination therapy with interferon-α and interleukin-2 in a patient with metastatic renal cell carcinoma

被引：0
作者：
Hosokawa, Y
Kishino, T
Ono, T
Oyama, N
Hayashi, K
Momose, H
机构：
[1] Hoshigaoka Koseinenkin Hosp, Dept Urol, Osaka 5738511, Japan
[2] Hoshigaoka Koseinenkin Hosp, Dept Hematol, Osaka 5738511, Japan
来源：
INTERNATIONAL JOURNAL OF UROLOGY | 2004年 / 11卷 / 10期
关键词：
autoimmunity; hemolytic anemia; interleukin-2;
D O I：
10.1111/j.1442-2042.2004.00914.x
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
Various toxicities have been observed during the treatment of advanced renal cell carcinoma with interferon-alpha (IFN-alpha) and/or interleukin-2 (IL-2). We report a case of severe anemia, which responded well to steroid therapy, in a patient receiving IL-2 plus IFN-alpha for metastatic renal cell carcinoma.
引用
收藏
页码：906 / 908
页数：3
相关论文
共 12 条
  • [1] HYPOTHYROIDISM AFTER TREATMENT WITH INTERLEUKIN-2 AND LYMPHOKINE-ACTIVATED KILLER CELLS
    ATKINS, MB
    MIER, JW
    PARKINSON, DR
    GOULD, JA
    BERKMAN, EM
    KAPLAN, MM
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 1988, 318 (24) : 1557 - 1563
  • [2] Buzio C, 2001, CANCER-AM CANCER SOC, V92, P2286, DOI 10.1002/1097-0142(20011101)92:9<2286::AID-CNCR1575>3.0.CO
  • [3] 2-I
  • [4] ALTERATION OF DACARBAZINE PHARMACOKINETICS AFTER INTERLEUKIN-2 ADMINISTRATION IN MELANOMA PATIENTS
    CHABOT, GG
    FLAHERTY, LE
    VALDIVIESO, M
    BAKER, LH
    [J]. CANCER CHEMOTHERAPY AND PHARMACOLOGY, 1990, 27 (02) : 157 - 160
  • [5] Dutcher JP, 1997, CANCER J, V3, pS73
  • [6] ETTINGHAUSEN SE, 1987, BLOOD, V69, P1654
  • [7] Renal-cell carcinoma
    Motzer, RJ
    Bander, NH
    Nanus, DM
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 1996, 335 (12) : 865 - 875
  • [8] Recombinant human interleukin-2, recombinant human interferon alfa-2a, or both in metastatic renal-cell carcinoma
    Negrier, S
    Escudier, B
    Lasset, C
    Douillard, JY
    Savary, J
    Chevreau, C
    Ravaud, A
    Mercatello, A
    Peny, J
    Mousseau, M
    Philip, T
    Tursz, T
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 1998, 338 (18) : 1272 - 1278
  • [9] PEREZ R, 1991, CANCER, V67, P2512, DOI 10.1002/1097-0142(19910515)67:10<2512::AID-CNCR2820671021>3.0.CO
  • [10] 2-5
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