Minimal stimulation using gonadotropin-releasing hormone (GnRH) antagonist and recombinant human follicle-stimulating hormone versus GnRH antagonist multiple-dose protocol in low responders undergoing in vitro fertilization/intracytoplasmic sperm injection

被引：26

作者：

Kim, Chung-Hoon ^{[1
]}

Kim, So-Ra ^{[1
]}

Cheon, Yong-Pil ^{[2
]}

Kim, Sung-Hoon ^{[1
]}

Chae, Hee-Dong ^{[1
]}

Kang, Byung-Moon ^{[1
]}

机构：

[1] Univ Ulsan, Dept Obstet & Gynecol, Coll Med, Div Reprod Endocrinol & Infertil,Asan Med Ctr, Seoul, South Korea

[2] Sungshin Womens Univ, Coll Nat Sci, Dept Biol, Seoul, South Korea

来源：

FERTILITY AND STERILITY | 2009年 / 92卷 / 06期

关键词：

MODIFIED NATURAL CYCLE; POOR RESPONDERS; FERTILIZATION; IVF;

D O I：

10.1016/j.fertnstert.2009.06.005

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

This prospective randomized study was performed to investigate the effectiveness of minimal stimulation using recombinant human FSH (rhFSH) and GnRH antagonist compared with GnRH antagonist multiple-dose protocol (MDP) in low responders undergoing IVF/intracytoplasmic sperm injection. Our study demonstrated that minimal stimulation in natural cycles provides similar pregnancy rates to the GnRH antagonist MDP with fewer dose and days of rhFSH used and thus can be a cost-effective alternative as a last chance before oocyte donation in low responders. (Fertil Steril(R) 2009;92:2082-4. (C)2009 by American Society for Reproductive Medicine.)

引用

页码：2082 / 2084

页数：3

共 6 条

[1] Outcome of in-vitro fertilization through natural cycles in poor responders [J].