Suppression of triple-negative breast cancer tumorigenesis by targeting cancer stem cells through JNK/Notch1 signaling inhibition

被引:1
|
作者
Xie, Xuemei [1 ]
Kaoud, Tamer S. [2 ]
Edupunganti, Ramakrishna [2 ]
Zhang, Tinghu [3 ]
Kogawa, Takahiro [4 ]
Chauhan, Gaurav B. [1 ]
Giannoukos, Dionysios N. [1 ]
Qi, Yuan [1 ]
Tripathy, Debu [1 ]
Gray, Nathanael S. [3 ]
Dalby, Kevin N. [2 ]
Bartholomeusz, Chandra [1 ]
Ueno, Naoto T. [1 ]
机构
[1] Univ Texas MD Anderson Canc Ctr, Houston, TX 77030 USA
[2] Univ Texas Austin, Austin, TX 78712 USA
[3] Harvard Univ, Sch Med, Boston, MA USA
[4] Natl Canc Ctr Hosp East, Kashiwa, Chiba, Japan
关键词
D O I
10.1158/1538-7445.AM2015-1505
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
1505
引用
收藏
页数:2
相关论文
共 50 条
  • [1] Targeting Notch signaling in cancer stem-like cells of triple-negative breast cancer
    Murphy, Adrienne M.
    Ucar, Ayse D.
    Miele, Lucio
    CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 2022, 31 (01)
  • [2] Specific inhibition of Notch1 signaling enhances the antitumor efficacy of chemotherapy in triple negative breast cancer through reduction of cancer stem cells
    Qiu, Ming
    Peng, Qinghai
    Jiang, Ivy
    Carroll, Christopher
    Han, Guangzhou
    Rymer, Isha
    Lippincott, John
    Zachwieja, Joseph
    Gajiwala, Ketan
    Kraynov, Eugenia
    Thibault, Stephane
    Stone, Donna
    Gao, Yijie
    Sofia, Susan
    Gallo, Jorge
    Li, Gang
    Yang, Jennifer
    Li, Kang
    Wei, Ping
    CANCER LETTERS, 2013, 328 (02) : 261 - 270
  • [3] Targeting Cancer Stem Cells in Triple-Negative Breast Cancer
    Park, So-Yeon
    Choi, Jang-Hyun
    Nam, Jeong-Seok
    CANCERS, 2019, 11 (07)
  • [4] Targeted inhibition of Notch1 gene enhances the killing effects of Paclitaxel on triple-negative breast cancer cells
    Zhou, Yu-Fu
    Sun, Qian
    Zhang, Ya-Jun
    Wang, Geng-Ming
    He, Bin
    Qi, Tao
    Zhou, Yan
    Li, Xing-Wang
    Li, Sheng
    He, Lin
    ASIAN PACIFIC JOURNAL OF TROPICAL MEDICINE, 2017, 10 (02) : 172 - 176
  • [5] Targeted inhibition of Notch1 gene enhances the killing effects of Paclitaxel on triple-negative breast cancer cells
    Yu-Fu Zhou
    Qian Sun
    Ya-Jun Zhang
    Geng-Ming Wang
    Bin He
    Tao Qi
    Yan Zhou
    Xing-Wang Li
    Sheng Li
    Lin He
    Asian Pacific Journal of Tropical Medicine, 2017, (02) : 172 - 176
  • [6] A molecular approach to triple-negative breast cancer: targeting the Notch signaling pathway
    Pardo, Isabele
    Fagundes, Pedro Brecheret
    de Oliveira, Rafael Santana
    Campregher, Paulo Vidal
    EINSTEIN-SAO PAULO, 2024, 22 : 1 - 6
  • [7] Targeting cancer stem-like cells in triple negative breast cancer cells through non-canonical notch signaling
    Hossain, Fokhrul
    Sorrentino, Claudia
    Bilyeu, Ayse
    Crabtree, Judy
    Pannuti, Antonio
    Golde, Todd
    Osborne, Barbara
    Miele, Lucio
    CANCER RESEARCH, 2017, 77
  • [8] Inhibition of Notch signaling enhances the antitumor efficacy of chemotherapy in triple negative breast cancer through reduction of cancer stem cells
    Wei, Ping
    Qiu, Ming
    Jiang, Ivy
    Carroll, Christopher
    Han, Guangzhou
    Rymer, Isha
    Kraynov, Eugenia
    Wu, Aidong
    Thibault, Stephane
    Stone, Donna
    Gao, Yijie
    Sofia, Susan
    Gallo, Jorge
    White, Janet
    Li, Gary
    Yang, Jennifer
    Los, Gerrit
    CANCER RESEARCH, 2012, 72
  • [9] Major vault protein is a direct target of Notch1 signaling and contributes to chemoresistance in triple-negative breast cancer cells
    Xiao, Ying-Sheng
    Zeng, De
    Liang, Yuan-Ke
    Wu, Yang
    Li, Mei-Fang
    Qi, Yu -Zhu
    Wei, Xiao-Long
    Huang, Wen-He
    Cheng, Min
    Zhang, Guo-Jun
    CANCER LETTERS, 2019, 440 : 156 - 167
  • [10] JNK-IN-8: a novel covalent inhibitor targeting JNK signaling in triple-negative breast cancer
    Xie, Xuemei
    Kaoud, Tamer S.
    Edupunganti, Ramakrishna
    Zhang, Tinghu
    Kogawa, Takahiro
    Chauhan, Gaurav B.
    Gray, Nathanael S.
    Bartholomeusz, Chandra
    Dalby, Kevin N.
    Ueno, Naoto T.
    CANCER RESEARCH, 2014, 74 (19)