Cytokine storm treated successfully with immunoglobulin therapy in a pregnant COVID-19 patient

被引:0
作者
Madaan, Sparsh [1 ]
Jaiswal, Arpita [1 ]
Kumar, Sunil [2 ]
Dewani, Deepika [1 ]
Talwar, Dhruv [2 ]
Khanna, Shivam [2 ]
机构
[1] Datta Meghe Inst Med Sci Deemed Univ, Jawaharlal Nehru Med Coll, Dept Obstet & Gynaecol, Wardha, Maharashtra, India
[2] Datta Meghe Inst Med Sci Deemed Univ, Jawaharlal Nehru Med Coll, Dept Med, Wardha, Maharashtra, India
关键词
COVID-19; pregnancy; immunoglobulin therapy;
D O I
暂无
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Ever since its emergence Severe Acute Respiratory Syndrome Coronavirus 2 (SARS CoV 2) has caused an enormous amount of morbidity and mortality. Pregnancy being a high risk state is also being affected by this lethal pandemic causing an increased risk of rising maternal mortality. The treatment strategies for managing COVID-19 in pregnant female remains limited with no definite treatment available. With the growing evidence of Lymphocytopenia in COVID-19 there has been a emergence of immunoglobulin (IVIg) as a relatively safe treatment option in immunodeficient states such as pregnancy. Though research remains limited in the aspect of immunoglobulin therapy in pregnancy a risk versus benefit ratio might allow use of immunoglobulin therapy. We present a case of COVID-19 associated cytokine storm with lymphocytopenia in a Pregnant female which was successfully treated with immunoglobulin therapy.
引用
收藏
页码:1413 / 1416
页数:4
相关论文
共 5 条
[1]  
Bashir S, 2020, Indian J Forensic Med Toxicol, V14, P638
[2]   Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records [J].
Chen, Huijun ;
Guo, Juanjuan ;
Wang, Chen ;
Luo, Fan ;
Yu, Xuechen ;
Zhang, Wei ;
Li, Jiafu ;
Zhao, Dongchi ;
Xu, Dan ;
Gong, Qing ;
Liao, Jing ;
Yang, Huixia ;
Hou, Wei ;
Zhang, Yuanzhen .
LANCET, 2020, 395 (10226) :809-815
[3]   COVID-19: what is next for public health? [J].
Heymann, David L. ;
Shindo, Nahoko ;
Bedford, Juliet ;
Enria, Delia ;
Giesecke, Johan ;
Heymann, David ;
Ihekweazu, Chikwe ;
Kobinger, Gary ;
Lane, Clifford ;
Memish, Ziad ;
Myoung-don, Oh ;
Sall, Amadou Alpha ;
Ungchusak, Kum ;
Wieler, Lothar .
LANCET, 2020, 395 (10224) :542-545
[4]  
Talwar D, 2021, MED SCI, V25, P1183
[5]   Interferons and Proinflammatory Cytokines in Pregnancy and Fetal Development [J].
Yockey, Laura J. ;
Iwasaki, Akiko .
IMMUNITY, 2018, 49 (03) :397-412