Are lifetime affective disorders predictive of long-term outcome in severe adolescent anorexia nervosa?

被引:33
|
作者
Carrot, B. [1 ,2 ,3 ]
Radon, L. [1 ,3 ]
Hubert, T. [1 ]
Vibert, S. [1 ,2 ]
Duclos, J. [1 ,3 ,4 ]
Curt, F. [1 ]
Godart, N. [1 ,2 ,3 ]
机构
[1] IMM, Dept Psychiat, 42 Blvd Jourdan, F-75014 Paris, France
[2] Paris Descartes Univ, Fac Med, Paris, France
[3] Univ Paris Sud, Univ Paris Saclay, UVSQ, CESP,INSERM, Villejuif, France
[4] Univ Paris Nanterre, UFR Psychol, CLIPSYD, EA 4430, Nanterre, France
关键词
Anorexia nervosa; Affective disorders; Predictive factors; Outcome; 10-YEAR FOLLOW-UP; BODY-MASS INDEX; EATING-DISORDERS; ANXIETY DISORDERS; BULIMIA-NERVOSA; COMORBIDITY; DEPRESSION; DIAGNOSES; SYMPTOMS; FAMILY;
D O I
10.1007/s00787-017-0963-5
中图分类号
B844 [发展心理学(人类心理学)];
学科分类号
040202 ;
摘要
Depression and anxiety are commonly associated with anorexia nervosa (AN) and contribute to difficulties in social integration, a negative factor for outcome in AN. The link between those disorders and AN has been poorly studied. Thus, our objective was to investigate (1) the link between outcome nine years after hospitalisation for AN and the occurrence of lifetime anxious or depressive comorbidities; (2) the prognostic value of these comorbidities on patient outcome; 181 female patients were hospitalised for AN (between 13 and 22 years old), and were re-evaluated for their psychological, dietary, physical and social outcomes, from 6 to 12 years after their hospitalisation. The link between anxious and depressive disorders (premorbid to AN and lifetime) and the outcome assessment criteria were tested through multivariate analyses; 63% of the participants had good or intermediate outcome, 83% had presented at least one anxiety or depression disorder in the course of their lives, half of them before the onset of AN. Premorbid obsessive compulsive disorders (OCD), BMI at admission, and premenarchal AN all contribute to poor prognosis. Social phobia and agoraphobia affect the subjects' quality of life and increase eating disorder symptoms. These results encourage a systematic assessment of, and care for, anxiety and depression comorbidities among female adolescent patients with a particular focus on premorbid OCD.
引用
收藏
页码:969 / 978
页数:10
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