PharmGKB very important pharmacogene: SLCO1B1

被引：59
作者：
Oshiro, Connie
Mangravite, Lara [2 ]
Klein, Teri [1 ]
Altman, Russ
机构：
[1] Stanford Univ, Med Ctr, Dept Genet, Stanford, CA 94305 USA
[2] Childrens Hosp Oakland, Res Inst, Oakland, CA 94609 USA
来源：
PHARMACOGENETICS AND GENOMICS | 2010年 / 20卷 / 03期
关键词：
OATP2; organic anion transporter; pharmacogenomics; pharmacokinetics; SLCO1B1; statins; ANION-TRANSPORTING POLYPEPTIDE; SINGLE NUCLEOTIDE POLYMORPHISMS; OATP-C SLC21A6; LIPID-LOWERING EFFICACY; HEPATIC-UPTAKE; SERUM BILIRUBIN; SELECTIVE ANTAGONIST; MAJOR DETERMINANT; PHARMACOKINETICS; PRAVASTATIN;
D O I：
10.1097/FPC.0b013e328333b99c
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
[No abstract available]
引用
收藏
页码：211 / 216
页数：6
相关论文
共 70 条
[1]   Identification of a novel gene family encoding human liver-specific organic anion transporter LST-1 [J].
Abe, T ;
Kakyo, M ;
Tokui, T ;
Nakagomi, R ;
Nishio, T ;
Nakai, D ;
Nomura, H ;
Unno, M ;
Suzuki, M ;
Naitoh, T ;
Matsuno, S ;
Yawo, H .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (24) :17159-17163
[2]   Interaction of oral antidiabetic drugs with hepatic uptake transporters -: Focus on organic anion transporting polypeptides and organic cation transporter 1 [J].
Bachmakov, Louri ;
Glaeser, Hartmut ;
Fromm, Martin F. ;
Koenig, Joerg .
DIABETES, 2008, 57 (06) :1463-1469
[3]   Differential interaction of 3-hydroxy-3-methylglutaryl-COA reductase inhibitors with ABCB1, ABCC2, and OATP1B1 [J].
Chen, CP ;
Mireles, RJ ;
Campbell, SD ;
Lin, J ;
Mills, JB ;
Xu, JHJ ;
Smolarek, TA .
DRUG METABOLISM AND DISPOSITION, 2005, 33 (04) :537-546
[4]   New insights into the pharmacodynamic and pharmacokinetic properties of statins [J].
Corsini, A ;
Bellosta, S ;
Baetta, R ;
Fumagalli, R ;
Paoletti, R ;
Bernini, F .
PHARMACOLOGY & THERAPEUTICS, 1999, 84 (03) :413-428
[5]   Association between a frequent allele of the gene encoding OATP1B1 and enhanced LDL-lowering response to fluvastatin therapy [J].
Couvert, Philippe ;
Giral, Philippe ;
Dejager, Sylvie ;
Gu, Jessie ;
Huby, Thierry ;
Chapman, M. John ;
Bruckert, Eric ;
Carrie, Alain .
PHARMACOGENOMICS, 2008, 9 (09) :1217-1227
[6]   Hepatic uptake of bilirubin and its conjugates by the human organic anion transporter SLC21A6 [J].
Cui, Y ;
König, J ;
Leier, I ;
Buchholz, U ;
Keppler, D .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2001, 276 (13) :9626-9630
[7]   The human organic anion transporter 3 (OAT3; SLC22A8):: genetic variation and functional genomics [J].
Erdman, AR ;
Mangravite, LM ;
Urban, TJ ;
Lagpacan, LL ;
Castro, RA ;
de la Cruz, M ;
Chan, W ;
Huang, CC ;
Johns, SJ ;
Kawamoto, M ;
Stryke, D ;
Taylor, TR ;
Carlson, EJ ;
Ferrin, TE ;
Brett, CM ;
Burchard, EG ;
Giacomini, KM .
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 2006, 290 (04) :F905-F912
[8]   Amino acid residues in transmembrane domain 10 of organic anion transporting polypeptide 1B3 are critical for cholecystokinin octapeptide transport [J].
Gui, Chunshan ;
Hagenbuch, Bruno .
BIOCHEMISTRY, 2008, 47 (35) :9090-9097
[9]   Effect of pregnane X receptor ligands on transport mediated by human OATP1B1 and OATP1B3 [J].
Gui, Chunshan ;
Miao, Yi ;
Thompson, Lucas ;
Wahlgren, Bret ;
Mock, Melissa ;
Stieger, Bruno ;
Hagenbuch, Bruno .
EUROPEAN JOURNAL OF PHARMACOLOGY, 2008, 584 (01) :57-65
[10]   The superfamily of organic anion transporting polypeptides [J].
Hagenbuch, B ;
Meier, PJ .
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 2003, 1609 (01) :1-18
1234567