Cocos nucifera (Coconut) water of different maturity stages affects hematological and coagulation parameters in rabbits: A positive lead

被引:0
作者
Rao, Sadia Saleem [1 ]
Ikram, Rahila [1 ]
机构
[1] Univ Karachi, Fac Pharm & Pharmaceut Sci, Dept Pharmacol, Karachi, Pakistan
关键词
Anemia; coconut water; coagulation; ANTICOAGULATION FACTORS; CHEMICAL-COMPOSITION;
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Cocos nucifera (coconut) water is a traditionally used beverage and sportsdrink around the world. The recommendations on the use of plants for different conditions often lack proper scientific research. This study is first of its kind to explore, compare and document scientific evidence of the effect of different stages cocos nucifera (coconut) water on hematological and coagulation parameters in rabbits. For this study, we selected healthy rabbits and used their blood samples for our target analysis. 4ml/100g of young and mature cocos nucifera (coconut) water was administered orally once a day to respective groups for 60 days. Control group was administered distilled water orally. Results showed positive effect of coconut water on key hematological parameters including red cells and hemoglobin. Coagulation profile revealed significant increase in platelets and fibrinogen level with decrease in bleeding time and increase in clotting time by coconut water. This study revealed slightly dominating profile of young coconut water over mature coconut water which may be attributed to the unique composition differences between young and mature coconut water including micronutrients, carbohydrates and phenolic components. Outcomes of this research lead to the speculation about possible effect of cocos nucifera (coconut) water in anemia and bleeding disorders.
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收藏
页码:1631 / 1634
页数:4
相关论文
共 17 条
  • [1] Bushra Riaz Bushra Riaz, 2013, Journal of Pharmacy Research, V7, P215, DOI 10.1016/j.jopr.2013.01.025
  • [2] Effect of diallyl trisulfide-rich garlic oil on blood coagulation and plasma activity of anticoagulation factors in rats
    Chan, Kung-chi
    Yin, Mei-chin
    Chao, Wan-ju
    [J]. FOOD AND CHEMICAL TOXICOLOGY, 2007, 45 (03) : 502 - 507
  • [3] EFFECTS OF LONG-TERM TREATMENT WITH WARFARIN ON FIBRINOGEN, FPA, TAT, AND D-DIMER IN PATIENTS WITH CORONARY-ARTERY DISEASE
    ERITSLAND, J
    SELJEFLOT, I
    ARNESEN, H
    SMITH, P
    WESTVIK, AB
    [J]. THROMBOSIS RESEARCH, 1992, 66 (01) : 55 - 60
  • [4] Protective value of Aloe vera against some toxic effects of arsenic in rats
    Gupta, R
    Flora, SJS
    [J]. PHYTOTHERAPY RESEARCH, 2005, 19 (01) : 23 - 28
  • [5] Khan MN, 2003, PAK J BOT, V35, P925
  • [6] Lee HW, 2014, INT J CLIN EXP PATHO, V7, P6179
  • [7] Cocos nucifera (L.) (Arecaceae): A phytochemical and pharmacological review
    Lima, E. B. C.
    Sousa, C. N. S.
    Meneses, L. N.
    Ximenes, N. C.
    Santos Junior, M. A.
    Vasconcelos, G. S.
    Lima, N. B. C.
    Patrocinio, M. C. A.
    Macedo, D.
    Vasconcelos, S. M. M.
    [J]. BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH, 2015, 48 (11) : 953 - 964
  • [8] p-coumaric acid, a common dietary phenol, inhibits platelet activity in vitro and in vivo
    Luceri, Cristina
    Giannini, Lucia
    Lodovici, Maura
    Antonucci, Emilia
    Abbate, Rosanna
    Masini, Emanuela
    Dolara, Piero
    [J]. BRITISH JOURNAL OF NUTRITION, 2007, 97 (03) : 458 - 463
  • [9] Phenolic Compounds, Antioxidant Activity, and Medium Chain Fatty Acids Profiles of Coconut Water and Meat at Different Maturity Stages
    Mahayothee, Busarakorn
    Koomyart, Intira
    Khuwijitjaru, Pramote
    Siriwongwilaichat, Prasong
    Nagle, Marcus
    Mueller, Joachim
    [J]. INTERNATIONAL JOURNAL OF FOOD PROPERTIES, 2016, 19 (09) : 2041 - 2051
  • [10] Prasad SS, 2012, INT J PHARM SCI RES, V3, P407