Efficient iron/copper co-catalyzed arylation of nitrogen nucleophiles

被引：315

作者：

Taillefer, Marc ^{[1
]}

Xia, Ning ^{[1
]}

Ouali, Armelle ^{[1
]}

机构：

[1] Ecole Natl Super Chim Montpellier, CNRS, UMR 5076, F-34296 Montpellier 5, France

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2007年 / 46卷 / 06期

关键词：

copper; cross-coupling; iron; nitrogen heterocycles;

D O I：

10.1002/anie.200603173

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Chemical Equation Presented) An ideal pair: Various substituted aryl halides react under mild conditions with nitrogen heterocycles in the presence of catalytic amounts of [Fe(acac)3] (acac = acetylacetonate) and copper salts to give the corresponding cross-coupling products in high yields (see scheme). This cheap and environmentally friendly cocatalyst system is the first example of cooperative Fe/Cu catalysis in this type of N-C bond formation. © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：934 / 936

页数：3

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