Efficient iron/copper co-catalyzed arylation of nitrogen nucleophiles

被引：315
作者：
Taillefer, Marc [1 ]
Xia, Ning [1 ]
Ouali, Armelle [1 ]
机构：
[1] Ecole Natl Super Chim Montpellier, CNRS, UMR 5076, F-34296 Montpellier 5, France
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2007年 / 46卷 / 06期
关键词：
copper; cross-coupling; iron; nitrogen heterocycles;
D O I：
10.1002/anie.200603173
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
(Chemical Equation Presented) An ideal pair: Various substituted aryl halides react under mild conditions with nitrogen heterocycles in the presence of catalytic amounts of [Fe(acac)3] (acac = acetylacetonate) and copper salts to give the corresponding cross-coupling products in high yields (see scheme). This cheap and environmentally friendly cocatalyst system is the first example of cooperative Fe/Cu catalysis in this type of N-C bond formation. © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.
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收藏
页码：934 / 936
页数：3
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