Epidemiologic profile of pediatric brain tumors in Morocco

被引:42
作者
Karkouri, Mehdi [2 ]
Zafad, Sadia [3 ]
Khattab, Mohammed [4 ]
Benjaafar, Noureddine [5 ]
El Kacemi, Hanan [5 ]
Sefiani, Sana [6 ]
Kettani, Fouad [7 ]
Dey, Subhojit [1 ]
Soliman, Amr S. [1 ]
机构
[1] Univ Michigan, Sch Publ Hlth, Dept Epidemiol, Ann Arbor, MI 48109 USA
[2] CHU Ibn Rochd, Dept Pathol, MA-20100 Casablanca, Morocco
[3] Hop 20 Aout 1953, Dept Hematol & Pediat Oncol, Casablanca, Morocco
[4] Rabat Childrens Hosp, Dept Pediat Hematol & Oncol, Rabat, Morocco
[5] Natl Inst Oncol, Rabat, Morocco
[6] Hop Special, Dept Pathol, Rabat, Morocco
[7] United Nations Ctr Pathol, Rabat, Morocco
关键词
Pediatric brain tumors; Central nervous system; Descriptive epidemiology; Morocco; Africa; NERVOUS-SYSTEM TUMORS; CHILDHOOD; CANCER; CLASSIFICATION; STATISTICS; CHILDREN; TRENDS;
D O I
10.1007/s00381-010-1097-y
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Brain tumors are the most common solid tumors diagnosed among children below 15 years worldwide. However, little is known about the profile of pediatric brain tumors in Africa. The purpose of this study was to further elaborate the epidemiological profile of pediatric brain tumors in Africa, specifically Morocco. A retrospective review was conducted of all patients with primary brain tumors in the age group 0-19 years, from 2003 to 2007, from multiple centers in two cities of Rabat and Casablanca, Morocco. Only patients with histopathological confirmation were included (n = 542). Descriptive epidemiologic profiles were created for the patients by age, sex, and histological subtypes of brain tumors. Overall medulloblastoma was the most common brain tumor (34.5%), followed by pilocytic astrocytoma (17.3%) and diffuse astrocytoma grade 2 (12.5%). Brain tumors occurred most commonly in 5-9-year age group followed by 10-14-year age group with the former being more common among males and the latter being more common among females. We also found medulloblastoma to be the most common brain tumor in the 0-14-year-olds. In this rare study focused on pediatric brain tumors in Morocco, most of the findings were consistent with past studies from other parts of the world. However, we found medulloblastoma to be the most common pediatric brain tumor followed by astrocytoma.
引用
收藏
页码:1021 / 1027
页数:7
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