Briarane diterpenoids from the Formosan Gorgonian coral Junceella fragilis

被引:28
作者
Sung, PJ [1 ]
Lin, MR [1 ]
Fang, LS [1 ]
机构
[1] Natl Museum Marine Biol & Aquarium, Checheng 944, Pingtung, Taiwan
关键词
Junceella fragilis; junceellolide; Gorgonian; briarane;
D O I
10.1248/cpb.52.1504
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
A new trihydroxy briarane-related diterpenoid, junceellolide 1 (1), along with a known metabolite, (1R,2R,5Z,7R,8S,9R,10R,12R,14R,17S)-2,14-diacetoxy-8,17-epoxy-9,12-dihydroxybriara-5,11(20)-dien-19-one (2), have been isolated from the gorgonian coral Junceella fragilis, collected off the southern Taiwan coast. The structure, including the relative configuration of the new compound 1, was elucidated by the combination of spectral data, particularly in high-resolution H-1- and C-13-NMR spectroscopy utilizing COSY, HMBC, HMQC, and NOESY experiments.
引用
收藏
页码:1504 / 1506
页数:3
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