Methods for the detection and identification of pathogenic bacteria: past, present, and future

被引：407

作者：

Varadi, Linda ^{[1
,2
]}

Luo, Jia Lin ^{[1
]}

Hibbs, David E. ^{[1
]}

Perry, John D. ^{[3
]}

Anderson, Rosaleen J. ^{[4
]}

Orenga, Sylvain ^{[5
]}

Groundwater, Paul W. ^{[1
]}

机构：

[1] Univ Sydney, Fac Pharm, Sydney, NSW 2006, Australia

[2] CSIRO Mfg, Res Way, Clayton, Vic 3168, Australia

[3] Freeman Rd Hosp, Microbiol Dept, Newcastle Upon Tyne, Tyne & Wear, England

[4] Univ Sunderland, Sunderland Pharm Sch, Sunderland, Durham, England

[5] BioMerieux Inc, Durham, NC USA

来源：

CHEMICAL SOCIETY REVIEWS | 2017年 / 46卷 / 16期

关键词：

DESORPTION IONIZATION-TIME; CLINICAL MICROBIOLOGY; RAPID IDENTIFICATION; ANTIMICROBIAL RESISTANCE; SAMPLE PREPARATION; GENOME; BLOOD; INFECTION; PCR; MICROORGANISMS;

D O I：

10.1039/c6cs00693k

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In order to retard the rate of development of antibacterial resistance, the causative agent must be identified as rapidly as possible, so that directed patient treatment and/or contact precautions can be initiated. This review highlights the challenges associated with the detection and identification of pathogenic bacteria, by providing an introduction to the techniques currently used, as well as newer techniques that are in development. Focusing on the chemical basis for these techniques, the review also provides a comparison of their advantages and disadvantages.

引用

页码：4818 / 4832

页数：15

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