A highly sensitive and selective turn-on fluorescent sensor for dihydrogen phosphate in living cells

被引:37
作者
Wang, Kun-Peng [1 ]
Zhang, Si-Jie [1 ]
Lv, Cheng-Dong [1 ]
Shang, Hui-Shi [1 ]
Jin, Zhi-Hui [1 ]
Chen, Shaojin [1 ]
Zhang, Qi [1 ]
Zhang, Yu-Bing [1 ]
Hu, Zhi-Qiang [1 ]
机构
[1] Qingdao Univ Sci & Technol, Coll Chem & Mol Engn, Minist Educ, Key Lab Eco Chem Engn, Qingdao 266042, Peoples R China
基金
中国国家自然科学基金;
关键词
Rhodamine; 6G; Naphthylurea conjugate; Dihydrophosphate; Fluorescent sensors; Live cell imaging; CHEMOSENSOR; PROBE; RECOGNITION; CONJUGATE; IONS;
D O I
10.1016/j.snb.2017.03.052
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
A novel visible light excitable chemosensor based on a rhodamine 6G naphthylurea conjugate was successfully synthesized, which shows highly selective and sensitive recognition ability toward H2PO4- in H2O-CH3CN (1/1, v/v). In response to H2PO4-, the probe provided remarkable fluorescence intensity change and clear color change from colorless to pink and the background anions showed small or no interference. The confocal fluorescent images demonstrated that the probe was cell-permeable and could effectively detect intracellular dihydrophosphate in living cells. (C) 2017 Elsevier B.V. All rights reserved.
引用
收藏
页码:791 / 796
页数:6
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