Prevalence of Chronic Complications, Their Risk Factors, and the Cardiovascular Risk Factors among Patients with Type 2 Diabetes Attending the Diabetic Clinic at a Tertiary Care Hospital in Sri Lanka

被引:36
作者
Arambewela, Maulee Hiromi [1 ,2 ]
Somasundaram, Noel P. [1 ]
Jayasekara, Hettiarachchige Buddhi Pradeep Ranjan [3 ]
Kumbukage, Mahesh P. [3 ]
Jayasena, Pulukkutti Mudiyanselage Sarath [1 ]
Chandrasekara, Chandrasekara Mudalige Priyanka Hemanthi [1 ]
Fernando, Kurukulasuriya Ravindra Alexis Sudath [1 ]
Kusumsiri, Divadalage Priyantha [1 ]
机构
[1] Natl Hosp Sri Lanka, Dept Diabet & Endocrinol, Colombo, Sri Lanka
[2] Univ Sri Jayewardenepura, Fac Med Sci, Nugegoda, Sri Lanka
[3] Minist Hlth, Colombo, Sri Lanka
关键词
HEART-DISEASE MORTALITY; UNITED-KINGDOM; SOUTH ASIANS; FOLLOW-UP; MELLITUS; EUROPEANS; OBESITY; EPIDEMIOLOGY; OVERWEIGHT; NEUROPATHY;
D O I
10.1155/2018/4504287
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Diabetes incurs heavy burden to patients and the healthcare system. Assessment of disease burden is important in taking necessary precautions and management decisions. We aimed to determine the prevalence of macro- and microvascular complications, their risk factors, and coronary artery disease (CAD) risk factors among patients with type 2 diabetes mellitus (T2DM). A descriptive cross-sectional single-centre study was carried out among 3000 patients with T2DM attending the diabetic clinic at the National Hospital of Sri Lanka from January to July 2016. The study population had 72.7% females and 27.3% males. Mean age and disease duration were 58.3 +/- 10.3 and 10.8 +/- 7 years, respectively. Prevalence of CAD, stroke, and peripheral vascular disease were 10.6%, 1.1%, and 4.7% while diabetic retinopathy, neuropathy, nephropathy, diabetic foot, and lower extremity amputation (LEA) were 26.1%, 62.6%, 50.8%, 2.6%, and 1.3%, respectively. Prevalence of overweight/obesity, hypertension, dyslipidemia, and smoking were 80%, 77.6%, 76.7%, and 11%, respectively. Increased age, disease duration, and HBA1c were risk factors for microvascular disease and diabetic foot while age was the only risk factor for macrovascular complications. Occurrence of CAD, peripheral neuropathy, diabetic foot, and LEA was significantly higher among males than when compared to females. This study highlights the major burden of chronic complications and high prevalence of CAD risk factors in this population.
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页数:10
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[11]   Do known risk factors explain the higher coronary heart disease mortality in South Asian compared with European men? Prospective follow-up of the Southall and Brent studies, UK [J].
Forouhi, N. G. ;
Sattar, N. ;
Tillin, T. ;
McKeigue, P. M. ;
Chaturvedi, N. .
DIABETOLOGIA, 2006, 49 (11) :2580-2588
[12]  
Gonsalves Wanda C, 2007, J S C Med Assoc, V103, P4
[13]   OBESITY AS AN INDEPENDENT RISK FACTOR FOR CARDIOVASCULAR-DISEASE - A 26-YEAR FOLLOW-UP OF PARTICIPANTS IN THE FRAMINGHAM HEART-STUDY [J].
HUBERT, HB ;
FEINLEIB, M ;
MCNAMARA, PM ;
CASTELLI, WP .
CIRCULATION, 1983, 67 (05) :968-977
[14]   SEX-HORMONES AND CORONARY-DISEASE - A REVIEW OF THE CLINICAL-STUDIES [J].
KALIN, MF ;
ZUMOFF, B .
STEROIDS, 1990, 55 (08) :330-352
[15]  
Kalofoutis Christos, 2007, Exp Clin Cardiol, V12, P17
[16]   Heterogeneity of Diabetes Outcomes Among Asians and Pacific Islanders in the US The Diabetes Study of Northern California (DISTANCE) [J].
Kanaya, Alka M. ;
Adler, Nancy ;
Moffet, Howard H. ;
Liu, Jennifer ;
Schillinger, Dean ;
Adams, Alyce ;
Ahmed, Ameena T. ;
Karter, Andrew J. .
DIABETES CARE, 2011, 34 (04) :930-937
[17]   Explaining the sex difference in coronary heart disease mortality among patients with type 2 diabetes mellitus - A meta-analysis [J].
Kanaya, AM ;
Grady, D ;
Barrett-Connor, E .
ARCHIVES OF INTERNAL MEDICINE, 2002, 162 (15) :1737-1745
[18]   Prevalence and projections of diabetes and pre-diabetes in adults in Sri Lanka - Sri Lanka Diabetes, Cardiovascular Study (SLDCS) [J].
Katulanda, P. ;
Constantine, G. R. ;
Mahesh, J. G. ;
Sheriff, R. ;
Seneviratne, R. D. A. ;
Wijeratne, S. ;
Wijesuriya, M. ;
McCarthy, M. I. ;
Adler, A. I. ;
Matthews, D. R. .
DIABETIC MEDICINE, 2008, 25 (09) :1062-1069
[19]   Prevalence of overweight and obesity in Sri Lankan adults [J].
Katulanda, P. ;
Jayawardena, M. A. R. ;
Sheriff, M. H. R. ;
Constantine, G. R. ;
Matthews, D. R. .
OBESITY REVIEWS, 2010, 11 (11) :751-756
[20]   Peripheral neuropathy in patients with diabetic foot ulcers: Clinical and nerve conduction study [J].
Kiziltan, Meral E. ;
Gunduz, Aysegul ;
Kiziltan, Gunes ;
Akalin, M. Ali ;
Uzun, Nurten .
JOURNAL OF THE NEUROLOGICAL SCIENCES, 2007, 258 (1-2) :75-79