Artificial Intelligence & Tissue Biomarkers: Advantages, Risks and Perspectives for Pathology

被引:28
|
作者
Lancellotti, Cesare [1 ,2 ]
Cancian, Pierandrea [3 ]
Savevski, Victor [3 ]
Kotha, Soumya Rupa Reddy [1 ,2 ]
Fraggetta, Filippo [4 ]
Graziano, Paolo [5 ]
Di Tommaso, Luca [1 ,2 ]
机构
[1] Humanitas Univ, Dept Biomed Sci, Via Rita Levi Montalcini 4, I-20090 Milan, Italy
[2] Humanitas Res Hosp, Pathol Unit, Via Manzoni 56, I-20089 Milan, Italy
[3] Humanitas Res Hosp, IRCCS, Artificial Intelligence Ctr, Via Manzoni 56, I-20089 Milan, Italy
[4] Cannizzaro Hosp, Dept Pathol, I-95021 Catania, Italy
[5] Fdn IRCCS Casa Sollievo Sofferenza, Pathol Unit, I-71013 San Giovanni Rotondo, FG, Italy
关键词
biomarker; artificial intelligence; pathology; personalized medicine; TUMOR-INFILTRATING LYMPHOCYTES; CONVOLUTIONAL NEURAL-NETWORKS; COMPUTER-EXTRACTED FEATURES; IMAGE-ANALYSIS; LUNG ADENOCARCINOMA; DIGITAL PATHOLOGY; PREDICT RESPONSE; PROSTATE-CANCER; DEEP; CLASSIFICATION;
D O I
10.3390/cells10040787
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Tissue Biomarkers are information written in the tissue and used in Pathology to recognize specific subsets of patients with diagnostic, prognostic or predictive purposes, thus representing the key elements of Personalized Medicine. The advent of Artificial Intelligence (AI) promises to further reinforce the role of Pathology in the scenario of Personalized Medicine: AI-based devices are expected to standardize the evaluation of tissue biomarkers and also to discover novel information, which would otherwise be ignored by human review, and use them to make specific predictions. In this review we will present how AI has been used to support Tissue Biomarkers evaluation in the specific field of Pathology, give an insight to the intriguing field of AI-based biomarkers and discuss possible advantages, risk and perspectives for Pathology.
引用
收藏
页数:12
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