Ultrasound-assisted one-pot, three-component synthesis of spiro[indoline-3,4′-pyrazolo[3,4-b]pyridine]-2,6′(1′H)-diones in water

被引：89

作者：

Bazgir, Ayoob ^{[1
]}

Ahadi, Somayeh ^{[1
]}

Ghahremanzadeh, Ramin ^{[1
]}

Khavasi, Hamid Reza ^{[1
]}

Mirzaei, Peiman ^{[1
]}

机构：

[1] Shahid Beheshti Univ, Dept Chem, Tehran, Iran

来源：

ULTRASONICS SONOCHEMISTRY | 2010年 / 17卷 / 02期

关键词：

Cumarin; Isatin; Pyrazole; Spirooxindole; Water; Ultrasound irradiation; MULTICOMPONENT REACTIONS; EFFICIENT SYNTHESIS; DERIVATIVES; ISATINS; SPIROOXINDOLES; CHEMISTRY; ISOCYANIDES; FACILE;

D O I：

10.1016/j.ultsonch.2009.09.009

中图分类号：

O42 [声学];

学科分类号：

070206 ; 082403 ;

摘要：

A simple, facile, efficient and three-component procedure for the synthesis of spiro[indoline-3,4'-pyrazolo[3,4-b]pyridine]-2,6'(1'H)-diones by the reaction of 4-hydroxycumarin, isatins and 1H-pyrazol-5-amines in water under ultrasonic irradiation is reported. The advantages of this method are the use of an inexpensive and readily available catalyst, easy work-up, good yields, and the use of water as a solvent that is considered to be relatively environmentally benign. (C) 2009 Elsevier B.V. All rights reserved.

引用

页码：447 / 452

页数：6

共 41 条

[1] Synthesis and evaluation of some new spiro indoline-based heterocycles as potentially active antimicrobial agents [J].