Association Between Multimorbidity and Depressive Symptom Among Community-Dwelling Elders in Eastern China

Purpose: This study aimed to investigate the prevalence of depressive symptoms and the association between multimorbidity and depressive symptoms among the elderly in eastern China. Patients and methods: A multicenter cross-sectional study was conducted in four cities (Jianggan, Yiwu and Anji in Zhejiang Province and Taixing in Jiangsu Province) in eastern China. We collected the information on 27 chronic conditions through the self-reported medical history and used the Geriatric Depression Scale (GDS) short form to evaluate depressive symptoms. Multivariate Logistic regression was used to evaluate the relationship between multimorbidity and depressive symptoms. Results: Five thousand two hundred and ninety-six participants were included into the current study, among which 2687 (50.74%) were female, with the mean +/- SD age 72.0 +/- 8.1 years old. The overall prevalence of depressive symptoms in eastern China was 23.5%. And the percentage of multimorbidity in depressed participants was higher compared with non-depressed participants (50.8% vs 38.8%, P<0.001). The univariate model and adjusted model suggested that participants with multiple chronic diseases were more likely to have a depressive symptom (adjusted OR=1.42; 95% CIs 1.19-1.70). Conclusion: Depressive symptom was significantly associated with multimorbidity among the community-dwelling elderly population in eastern China.