Leaving Group Property of Dimethyl Sulfide

被引：18

作者：

Jurie, Sandra ^{[1
]}

Denegri, Bernard ^{[1
]}

Kronja, Olga ^{[1
]}

机构：

[1] Univ Zagreb, Fac Pharm & Biochem, Zagreb 10000, Croatia

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2010年 / 75卷 / 11期

关键词：

(4-METHOXYBENZYL)DIMETHYLSULFONIUM CHLORIDE; BENZHYDRYL DERIVATIVES; SOLVOLYSIS; SCALE; ION; NUCLEOFUGALITY; RATES; REACTIVITY;

D O I：

10.1021/jo100327c

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The LFER equation log k = S(1)( E(f) + N(f)) was used to derive the nucleofuge specific parameters (N(f) and S(f)) for dimethyl sulfide in the series of aqueous alcohols, using the S(N)l solvolysis rate constants obtained for X-substituted benzhydryl dimethyl sulfonates 1-5. The slope parameters (s(f)) are practically independent of the solvent used, while N(f) parameters slightly decrease as the polarity of the solvent increases.

引用

页码：3851 / 3854

页数：4

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