Iron-catalyzed 1,6-addition of aryl Grignard reagents to 2,4-dienoates and -dienamides

被引：66

作者：

Fukuhara, K ^{[1
]}

Urabe, H ^{[1
]}

机构：

[1] Tokyo Inst Technol, Dept Biomol Engn, Midori Ku, Yokohama, Kanagawa 2268501, Japan

来源：

TETRAHEDRON LETTERS | 2005年 / 46卷 / 04期

关键词：

Grignard reagents; iron; 1,6-addition; 2,4-dienoate and -dienamide; cis-olefin;

D O I：

10.1016/j.tetlet.2004.11.131

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

1, 6-Addition of aryl Grignard reagents to 2,4-dienoates or -dienamides was nicely catalyzed by iron salt to give 5-aryl-3-enoates or the corresponding amides in a highly regio- and stercoselective manner. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：603 / 606

页数：4