The synthesis of angularly fused tricyclic compounds via tandem ring closing metathesis reactions

被引：32

作者：

Bassindale, MJ

Edwards, AS

Hamley, P

Adams, H

Harrity, JPA

机构：

[1] Univ Sheffield, Dept Chem, Sheffield S3 7HF, S Yorkshire, England

[2] AstraZeneca Res & Dev, Dept Med Chem, Loughborough LE11 5RH, Leics, England

来源：

CHEMICAL COMMUNICATIONS | 2000年 / 12期

关键词：

D O I：

10.1039/b002136i

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A novel and highly efficient approach to angularly fused tricycles has been developed through the employment of selective tandem ring closing metathesis reactions.

引用

页码：1035 / 1036

页数：2

共 16 条

[1]

Armstrong SK, 1998, J CHEM SOC PERK T 1, P371

[2] Spirocycle assembly through selective tandem ring closing metathesis reactions [J].

Bassindale, MJ ;

Hamley, P ;

Leitner, A ;

Harrity, JPA .

TETRAHEDRON LETTERS, 1999, 40 (16) :3247-3250

[3] Bis ring closing olefin metathesis for the synthesis of unsaturated polycyclic ethers. O-membered ring cyclization in favor of C-membered ring cyclization [J].

Baylon, C ;

Heck, MP ;

Mioskowski, C .

JOURNAL OF ORGANIC CHEMISTRY, 1999, 64 (09) :3354-3360

[4] Synthesis of a C(22)-C(34) halichondrin B precursor via ring opening double ring closing metathesis [J].

Burke, SD ;

Quinn, KJ ;

Chen, VJ .

JOURNAL OF ORGANIC CHEMISTRY, 1998, 63 (24) :8626-8627

[5] Recent advances in olefin metathesis and its application in organic synthesis [J].

Grubbs, RH ;

Chang, S .

TETRAHEDRON, 1998, 54 (18) :4413-4450

[6]

Hoveyda AH, 1998, TOP ORGANOMETAL CHEM, V1, P105

[7] Spiro-annulation via ring closing metathesis reaction [J].

Kotha, S ;

Manivannan, E ;

Ganesh, T ;

Sreenivasachary, N ;

Deb, A .

SYNLETT, 1999, (10) :1618-1620

[8]

Lautens M, 1999, ANGEW CHEM INT EDIT, V38, P129, DOI 10.1002/(SICI)1521-3773(19990115)38:1/2<129::AID-ANIE129>3.0.CO

[9]

2-I

[10] Synthesis of polyquinane natural products: An update [J].

Mehta, G ;

Srikrishna, A .

CHEMICAL REVIEWS, 1997, 97 (03) :671-719

← 1 2 →