Impaired c-Met Receptor Degradation Mediated by MET Exon 14 Mutations in Non-Small-Cell Lung Cancer

[1] Met/hepatocyte growth factor receptor ubiquitination suppresses transformation and is required for Hrs phosphorylation [J]. MOLECULAR AND CELLULAR BIOLOGY, 2005, 25 (21) : 9632 - 9645

[2] ROS1 Rearrangements Define a Unique Molecular Class of Lung Cancers [J]. JOURNAL OF CLINICAL ONCOLOGY, 2012, 30 (08) : 863 - 870

[3] Nivolumab versus Docetaxel in Advanced Squamous-Cell Non-Small-Cell Lung Cancer [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2015, 373 (02) : 123 - 135

[4] Cancer Genome Atlas Research Network, 2018, Nature, V559, pE12, DOI [10.1038/nature13385, 10.1038/s41586-018-0228-6]

[5] Increased MET Gene Copy Number Negatively Affects Survival of Surgically Resected Non-Small-Cell Lung Cancer Patients [J]. JOURNAL OF CLINICAL ONCOLOGY, 2009, 27 (10) : 1667 - 1674

[6] Comprehensive molecular profiling of lung adenocarcinoma [J]. NATURE, 2014, 511 (7511) : 543 - 550

[7] MET Gene Copy Number Predicts Worse Overall Survival in Patients with Non-Small Cell Lung Cancer (NSCLC); A Systematic Review and Meta-Analysis [J]. PLOS ONE, 2014, 9 (09):

[8] MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling [J]. SCIENCE, 2007, 316 (5827) : 1039 - 1043

[9] Activation of MET via Diverse Exon 14 Splicing Alterations Occurs in Multiple Tumor Types and Confers Clinical Sensitivity to MET Inhibitors [J]. CANCER DISCOVERY, 2015, 5 (08) : 850 - 859

[10] Targeting MET in cancer: rationale and progress [J]. NATURE REVIEWS CANCER, 2012, 12 (02) : 89 - 103

[1] Met/hepatocyte growth factor receptor ubiquitination suppresses transformation and is required for Hrs phosphorylation [J]. MOLECULAR AND CELLULAR BIOLOGY, 2005, 25 (21) : 9632 - 9645

[2] ROS1 Rearrangements Define a Unique Molecular Class of Lung Cancers [J]. JOURNAL OF CLINICAL ONCOLOGY, 2012, 30 (08) : 863 - 870

[3] Nivolumab versus Docetaxel in Advanced Squamous-Cell Non-Small-Cell Lung Cancer [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2015, 373 (02) : 123 - 135

[4] Cancer Genome Atlas Research Network, 2018, Nature, V559, pE12, DOI [10.1038/nature13385, 10.1038/s41586-018-0228-6]

[5] Increased MET Gene Copy Number Negatively Affects Survival of Surgically Resected Non-Small-Cell Lung Cancer Patients [J]. JOURNAL OF CLINICAL ONCOLOGY, 2009, 27 (10) : 1667 - 1674

[6] Comprehensive molecular profiling of lung adenocarcinoma [J]. NATURE, 2014, 511 (7511) : 543 - 550

[7] MET Gene Copy Number Predicts Worse Overall Survival in Patients with Non-Small Cell Lung Cancer (NSCLC); A Systematic Review and Meta-Analysis [J]. PLOS ONE, 2014, 9 (09):

[8] MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling [J]. SCIENCE, 2007, 316 (5827) : 1039 - 1043

[9] Activation of MET via Diverse Exon 14 Splicing Alterations Occurs in Multiple Tumor Types and Confers Clinical Sensitivity to MET Inhibitors [J]. CANCER DISCOVERY, 2015, 5 (08) : 850 - 859

[10] Targeting MET in cancer: rationale and progress [J]. NATURE REVIEWS CANCER, 2012, 12 (02) : 89 - 103