Myricetin: A comprehensive review on its biological potentials

被引：120

作者：

Imran, Muhammad ^{[1
]}

Saeed, Farhan ^{[2
]}

Hussain, Ghulam ^{[3
]}

Imran, Ali ^{[2
]}

Mehmood, Zaffar ^{[4
]}

Gondal, Tanweer Aslam ^{[5
]}

El-Ghorab, Ahmed ^{[6
]}

Ahmad, Ishtiaque ^{[7
]}

Pezzani, Raffaele ^{[8
,9
]}

Arshad, Muhammad Umair ^{[2
]}

Bacha, Umar ^{[10
]}

Shariarti, Mohammad Ali ^{[11
]}

Rauf, Abdur ^{[12
]}

Muhammad, Naveed ^{[13
]}

Shah, Zafar Ali ^{[12
]}

Zengin, Gokhan ^{[14
]}

Islam, Saiful ^{[15
]}

机构：

[1] Univ Lahore, Univ Inst Diet & Nutr Sci, Fac Allied Hlth Sci, Lahore, Pakistan

[2] Govt Coll Univ, Inst Home & Food Sci, Dept Food Sci, Faisalabad, Pakistan

[3] Govt Coll Univ, Fac Life Sci, Dept Physiol, Neurochemicalbiol & Genet Lab NGL, Faisalabad, Pakistan

[4] Forman Christian Coll Chartered Univ, Sch Life Sci, Lahore, Pakistan

[5] Deakin Univ, Fac Hlth, Sch Exercise & Nutr, Burwood, Vic, Australia

[6] Jouf Univ, Coll Sci, Chem Dept, Sakaka, Saudi Arabia

[7] Univ Vet & Anim Sci, Dept Dairy Technol, Lahore, Pakistan

[8] Univ Padua, Dept Med DIMED, Endocrinol Unit, Padua, Italy

[9] Assoc Italiana Ric Oncol Base, AIROB, Padua, Italy

[10] Univ Management & Technol, Sch Hlth Sci SHS, Lahore, Pakistan

[11] Moscow State Univ Technol & Management First Coss, Dept Technol Food Prod, Moscow, Russia

[12] Univ Swabi, Dept Chem, Swabi, Khyber Pakhtunk, Pakistan

[13] Abdul Wall Khan Univ, Dept Pharm, Mardan, Pakistan

[14] Selcuk Univ, Sci Fac, Dept Biol, Konya, Turkey

[15] Univ Dhaka, Inst Nutr & Food Sci, Dhaka, Bangladesh

来源：

FOOD SCIENCE & NUTRITION | 2021年 / 9卷 / 10期

关键词：

anticancer; antidiabetic; Myricaceae; Myricetin; phytochemical; CELL-CYCLE ARREST; HOVENIA-DULCIS THUNB; THYROID-CANCER CELLS; OXIDATIVE STRESS; MITOCHONDRIAL DYSFUNCTION; INHIBITS PROLIFERATION; FLAVONOID MYRICETIN; ANTICANCER ACTIVITY; INSULIN-RESISTANCE; ALPHA-GLUCOSIDASE;

D O I：

10.1002/fsn3.2513

中图分类号：

TS2 [食品工业];

学科分类号：

0832 ;

摘要：

Myricetin is a critical nutritive component of diet providing immunological protection and beneficial for maintaining good health. It is found in fruits, vegetables, tea, and wine. The families Myricaceae, Polygonaceae, Primulaceae, Pinaceae, and Anacardiaceae are the richest sources of myricetin. Different researchers explored the therapeutic potential of this valuable constituent such as anticancer, antidiabetic, antiobesity, cardiovascular protection, osteoporosis protection, anti-inflammatory, and hepatoprotective. In addition to these, the compound has been tested for cancer and diabetic mellitus during clinical trials. Health benefits of myricetin are related to its impact on different cell processes, such as apoptosis, glycolysis, cell cycle, energy balance, lipid level, serum protein concentrations, and osteoclastogenesis. This review explored the potential health benefits of myricetin with a specific emphasis on its mechanism of action, considering the most updated and novel findings in the field.

引用

页码：5854 / 5868

页数：15

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