ZnO nano-cages derived from ZIF-8 with enhanced anti mycobacterium-tuberculosis activities

被引:28
作者
Cui, Junwei [1 ]
Wang, Le [2 ]
Han, Yongqin [4 ]
Liu, Weiguo [1 ]
Li, Zhenyun [1 ]
Guo, Zheng [5 ]
Hu, Yuansen [2 ]
Chang, Zheng [3 ]
Yuan, Qipeng [3 ]
Wang, Jinshui [2 ]
机构
[1] Xinxiang Med Univ, Dept TB 1, Affiliated Hosp 1, Weihui, Henan, Peoples R China
[2] Henan Univ Technol, Sch Biol Engn, Zhengzhou, Henan, Peoples R China
[3] Beijing Univ Chem Technol, State Key Lab Chem Resource Engn, Beijing, Peoples R China
[4] Shandong Univ Sci & Technol, Coll Mat Sci & Engn, Dept Polymer Mat, Qingdao 266510, Peoples R China
[5] Zhongyuan Univ Technol, Coll Text, Zhengzhou, Henan, Peoples R China
基金
美国国家科学基金会;
关键词
ZnO; Nanoparticles; Hollow structures; MOFs; Anti-bacteria; SENSITIZED SOLAR-CELLS; ZEOLITIC IMIDAZOLATE FRAMEWORKS; LITHIUM-ION BATTERIES; ZINC-OXIDE NANOPARTICLES; METAL-ORGANIC FRAMEWORKS; PHOTOCATALYTIC ACTIVITY; ANTIBACTERIAL ACTIVITY; ESCHERICHIA-COLI; OXIDATIVE STRESS; ANODE MATERIAL;
D O I
10.1016/j.jallcom.2018.06.339
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
A facile and reproducible method was proposed to synthesize ZnO nano-cages (ZNC) using zeolitic imidazolate framework-8 (ZIF-8) as precursor. The ZNCs were in situ formed taking advantage of the uniform shape of the ZIF-8. The shape, size, crystal structure and composition of the ZNCs were confirmed with scanning/transmission electron microscope, X-ray diffraction, and X-ray photoelectron spectroscopy, which indicates the structural qualities of the ZNCs is highly sensitive to the conversion heating process. In addition, based on the microplate alamar blue assay technique, the ZNC-400 shows the optimized effects on inhibiting the growth of M. tuberculosis. The minimum inhibitory concentration could be measured as 12.5 mu g/mL, which is similar with the effect of the commercial organic medicines, indicating the novel ZNC has great potential to function as positive candidate for the organic medicines to combat tuberculosis disease. (C) 2018 Elsevier B.V. All rights reserved.
引用
收藏
页码:619 / 625
页数:7
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