Effect of nitro derivatives on electromechanical coupling in ureteral smooth muscle cells

被引：0

作者：

Kovalev, IV ^{[1
]}

Popov, AG ^{[1
]}

Panov, AA ^{[1
]}

Borodin, YL ^{[1
]}

Kapilevich, LV ^{[1
]}

Anfinogenova, YD ^{[1
]}

Baskakov, MB ^{[1
]}

Medvedev, MA ^{[1
]}

机构：

[1] Siberian Med Univ, Dept Normal Physiol, Dept Biophys, Tomsk, Russia

来源：

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2000年 / 129卷 / 05期

关键词：

smooth muscle cells; nitro derivatives; ionic membrane; permeability;

D O I：

10.1007/BF02439800

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Double sucrose gap experiments revealed differences in the effect of nitroglycerin and sodium nitroprusside on action potential and contraction of ureteral smooth muscle cells. Unlike sodium nitroprusside, nitroglycerin inhibited voltage-dependent Ca2+ membrane permeability. It was concluded that cGMP-independent mechanisms of the effects of nitro derivative reflect the peculiarities of excitation-contraction coupling in smooth muscles.

引用

页码：455 / 457

页数：3

共 15 条

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