Anaphylactic Reaction to Lansoprazole: Case Report

Anaphylaxis is a serious systemic allergic reaction to allergens. A 57-year-old woman applied to emergency unit with facial redness and difficulty in breathing after she swallowed a 30 mg lansoprazole capsule 15 minutes ago. She was agitated and had dyspnea. The patient was treated and followed up in the emergency unit. Anaphylaxis was primarily diagnosed by the clinical history and acutely treated in emergency unit.. There are no reliable and practical laboratory tests to diagnose anaphylaxis. Proton pump inhibitors, which are widely used for the treatment of peptic ulcer, are associated with a low incidence of adverse reactions. There are three reported cases of lansoprazole anaphylaxis occurred during challenge tests. Anaphylactic reactions to proton pump inhibitors are rare but they should be kept in mind.