A case of disseminated Langerhans' cell histiocytosis treated with thalidomide

被引：9
|
作者：
Mauro, E
Fraulini, C
Rigolin, GM
Galeotti, R
Spanedda, R
Castoldi, G
机构：
[1] Univ Ferrara, Dept Biomed Sci, Sect Hematol, I-44100 Ferrara, Italy
[2] Univ Ferrara, Dept Surg Anaesthesiol & Radiol Sci, I-44100 Ferrara, Italy
来源：
EUROPEAN JOURNAL OF HAEMATOLOGY | 2005年 / 74卷 / 02期
关键词：
Langerhans' cell histiocytosis; lung; thalidomide;
D O I：
10.1111/j.1600-0609.2004.00358.x
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Tumor necrosis factor alpha (TNF-alpha) seems to play a key role in the pathogenesis of Langerhans' cell histiocytosis (LCH). Thalidomide is an immunomodulator agent of inflammatory cytokines including TNF-alpha. To our knowledge this is the first case of disseminated LCH successfully treated with thalidomide.
引用
收藏
页码：172 / 174
页数：3
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