Propofol and the electroencephalogram

被引：65
作者：
San-juan, Daniel [1 ]
Chiappa, Keith H. [1 ]
Cole, Andrew J. [1 ]
机构：
[1] Massachusetts Gen Hosp, Neurophysiol Serv, Boston, MA 02114 USA
来源：
CLINICAL NEUROPHYSIOLOGY | 2010年 / 121卷 / 07期
关键词：
EEG; Electroencephalogram; Propofol; Anesthetics; Sedation; REFRACTORY STATUS EPILEPTICUS; RAT HIPPOCAMPAL SLICES; SEIZURE-LIKE PHENOMENA; INTENSIVE-CARE UNIT; ELECTROCONVULSIVE-THERAPY; BURST-SUPPRESSION; ANESTHETIC AGENTS; TRACHEAL INTUBATION; BISPECTRAL INDEX; SPECTRAL ENTROPY;
D O I：
10.1016/j.clinph.2009.12.016
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Propofol is an emulsion formulation of 2,6 diisopropylphenol developed in 1975. Widely recognized, it offers beneficial effects compared with other sedative drugs. Propofol is used in several clinical situations including multiple surgical procedures and critical-care medical conditions. Since technological advances over recent years have allowed an ever-increasing number of patients undergoing propofol therapy to be monitored by using continuous digital EEG, it is important to have a complete understanding of the effects of propofol on EEG in diverse clinical scenarios. This paper presents a review of the effects of propofol in electroencephalograms and discusses proconvulsive, anticonvulsive proprieties and the EEG findings in different medical conditions. (C) 2009 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码：998 / 1006
页数：9
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