Activation of Pgc1α by EET Stimulates Insulin Sensitivity, Normalizes Blood Pressure and Increases Mitochondrial Oxphos in Obese Mice

被引:0
|
作者
Singh, Shailendra P.
Waldman, Maayan
Schragenheim, Joseph
Bellner, Lars
Cao, Jian
Arad, Michael
Hochhauser, Edith
Abraham, Nader
机构
关键词
D O I
暂无
中图分类号
R6 [外科学];
学科分类号
1002 ; 100210 ;
摘要
P172
引用
收藏
页数:2
相关论文
共 34 条
  • [21] APOLIPOPROTEIN A-1 MIMETIC PEPTIDES L-4F TREATMENT REDUCES ADIPOSITY INCREASES ADIPONECTIN LEVELS AND INSULIN SENSITIVITY IN OBESE MICE
    Abraham, Nader G.
    Vanella, Luca
    Ikehara, Susumu
    JOURNAL OF PHYSIOLOGICAL SCIENCES, 2009, 59 : 414 - 414
  • [22] Activation of the AMPK/Sirt1 pathway by a leucine-metformin combination increases insulin sensitivity in skeletal muscle, and stimulates glucose and lipid metabolism and increases life span in Caenorhabditis elegans
    Banerjee, Jheelam
    Bruckbauer, Antje
    Zemel, Michael B.
    METABOLISM-CLINICAL AND EXPERIMENTAL, 2016, 65 (11): : 1679 - 1691
  • [23] Activation of Sirtuin1 (SIRT1) by the Novel Small Molecule SRT2104 Promotes Body Weight Loss, Increases Exercise Capacity and Improves Insulin Sensitivity in Diet-Induced Obese Mice
    Qi, Yong
    Davis, Meghan L.
    Hirsch, Michael L.
    Cote, Angela M.
    Lainez, Elden O.
    Johnson, Marc O.
    Gagne, David J.
    Vlasuk, George P.
    Ellis, James L.
    DIABETES, 2010, 59 : A104 - A104
  • [24] Alpha-lipoic acid attenuates silica-induced pulmonary fibrosis by improving mitochondrial function via AMPK/PGC1α pathway activation in C57BL/6J mice
    Chang, Meiyu
    Xu, Guangcui
    Xiong, Cheng
    Yang, Xuesi
    Yan, Sensen
    Tao, Yingjun
    Li, Haibin
    Li, Yuchun
    Yao, Sanqiao
    Zhao, Yingzheng
    TOXICOLOGY LETTERS, 2021, 350 : 121 - 132
  • [25] Chronic Angiotensin-(1-7) Improves Insulin Sensitivity in High-Fat Fed Mice Independent of Blood Pressure
    Williams, Ian M.
    Otero, Yolanda F.
    Bracy, Deanna P.
    Wasserman, David H.
    Biaggioni, Italo
    Arnold, Amy C.
    HYPERTENSION, 2016, 67 (05) : 983 - 991
  • [26] Ablation of Soluble Epoxide Hydrolase Expression Increases Beige Fat Over White Fat Through an Increase in Mitochondrial Integrity, Insulin Sensitivity and HO-1-PGC1α-adiponectin in-vitro and in-vivo
    Liu, Lu
    Vanella, Luca
    Bradbury, J. Alyce
    Zeldin, Darryl C.
    Abraham, Nader G.
    FASEB JOURNAL, 2018, 32 (01):
  • [27] Activation of prostaglandin E2 EP1 receptor increases arteriolar tone and blood pressure in mice with type 2 diabetes
    Rutkai, Ibolya
    Feher, Attila
    Erdei, Nora
    Henrion, Daniel
    Papp, Zoltan
    Edes, Istvan
    Koller, Akos
    Kaley, Gabor
    Bagi, Zsolt
    CARDIOVASCULAR RESEARCH, 2009, 83 (01) : 148 - 154
  • [28] Chronic AT2 receptor activation increases renal ACE2 activity, attenuates AT1 receptor function and blood pressure in obese Zucker rats
    Ali, Quaisar
    Wu, Yonnie
    Hussain, Tahir
    KIDNEY INTERNATIONAL, 2013, 84 (05) : 931 - 939
  • [29] Antisense protein tyrosine phosphatase 1B lowers plasma glucose, increases insulin sensitivity and reverses activation of the stress kinase p38 in ob/ob mice.
    Gum, RJ
    Zinker, B
    Rondinone, C
    Clampit, J
    Waring, J
    Gaede, L
    Stark, M
    Heindel, M
    Xie, N
    Trevillyan, J
    Jirousek, M
    Ulrich, R
    DIABETOLOGIA, 2001, 44 : A78 - A78
  • [30] Coupling factor 6-induced activation of ecto-F1Fo complex induces insulin resistance, mild glucose intolerance and elevated blood pressure in mice
    Osanai, T.
    Tanaka, M.
    Magota, K.
    Tomita, H.
    Okumura, K.
    DIABETOLOGIA, 2012, 55 (02) : 520 - 529