Should tranexamic acid be used for 3 days after total knee replacement? A randomized study in 250 patients

被引：0

作者：

Shah, Nilen ^{[1
]}

Khetan, Vatsal ^{[1
]}

Sivanadan, Hari ^{[1
]}

机构：

[1] Smt SR Mehta & Sir KP Cardiac Inst, Mumbai, Maharashtra, India

来源：

ACTA ORTHOPAEDICA BELGICA | 2021年 / 87卷 / 04期

关键词：

Tranexamic acid; total knee replacement; routes; duration; PRIMARY TOTAL HIP; BLOOD-LOSS; ARTHROPLASTY; TRANSFUSION; EFFICACY; HEMOGLOBIN; REDUCTION; REGIMEN; SAFE;

D O I：

暂无

中图分类号：

R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];

学科分类号：

摘要：

The aim is to study whether a 3 day course of Tranexamic acid (TXA) is more effective in reducing blood loss following a TKR than a 1 day course. 250 patients were prospectively randomised into Group A (n=138; Perioperative and additional oral TXA for two days) and Group B (n=112; only perioperative TXA). Total Blood loss was calculated by the Haemoglobin (Hb) loss method at 4 days and compared in both groups using Mann Whitney test. The mean perioperative blood loss in group A was 631.69 +/- 264.99 ml as compared to 685.55 +/- 239.033 ml in group B (p=0.0434). Use of TXA for 3 days following a TKR can be more effective in reducing blood loss.

引用

页码：697 / 703

页数：7

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