Amyloid Heart Disease

被引：157

作者：

Falk, Rodney H. ^{[1
]}

Dubrey, Simon W. ^{[2
]}

机构：

[1] Harvard Univ, Sch Med, Harvard Vanguard Med Associates, Boston, MA 02215 USA

[2] Hillingdon Hosp Uxbridge, Uxbridge, Middx, England

来源：

PROGRESS IN CARDIOVASCULAR DISEASES | 2010年 / 52卷 / 04期

关键词：

Amyloidosis; Biochemical typing; Cardiac deposition; PRIMARY SYSTEMIC AMYLOIDOSIS; CARDIOVASCULAR MAGNETIC-RESONANCE; STEM-CELL TRANSPLANTATION; LIGHT-CHAIN AMYLOIDOSIS; ORTHOTOPIC LIVER-TRANSPLANTATION; MELPHALAN PLUS DEXAMETHASONE; SEVERE CARDIAC AMYLOIDOSIS; BRAIN NATRIURETIC PEPTIDE; LANDMARK CLINICAL-TRIAL; AL PRIMARY AMYLOIDOSIS;

D O I：

10.1016/j.pcad.2009.11.007

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The systemic amyloidoses are an uncommon group of disorders characterized by the extracellular deposition of amyloid in one or more organs. Cardiac deposition, leading to an infiltrative/restrictive cardiomyopathy, is a common feature of amyloidosis. It may be the presenting feature of the disease or may be discovered while investigating a patient presenting with non-cardiac amyloidosis. In this article we review the features of cardiac amyloidosis and its varied manifestations. The need for a high index of suspicion and the critical importance of precise biochemical typing of the amyloid deposits is stressed in light of recent advances in therapy which can, when appropriately used, significantly improve prognosis. (Prog Cardiovasc Dis 2010;52:347-361) (C) 2010 Elsevier Inc. All rights reserved.

引用

页码：347 / 361

页数：15

共 136 条

[1] Systemic amyloidosis presenting with angina pectoris [J].

Al Suwaidi, J ;

Velianou, JL ;

Gertz, MA ;

Cannon, RO ;

Higano, ST ;

Holmes, DR ;

Lerman, A .

ANNALS OF INTERNAL MEDICINE, 1999, 131 (11) :838-841

[2]

Almeida M. R., 2005, Current Drug Targets - CNS and Neurological Disorders, V4, P587, DOI 10.2174/156800705774322076

[3] Fine-needle aspiration of abdominal fat pad for amyloid detection: A clinically useful test? [J].

Ansari-Lari, MA ;

Ali, SZ .

DIAGNOSTIC CYTOPATHOLOGY, 2004, 30 (03) :178-181

[4] CARDIAC IMMUNOCYTE-DERIVED (AL) AMYLOIDOSIS - AN ENDOMYOCARDIAL BIOPSY STUDY IN 11 PATIENTS [J].

ARBUSTINI, E ;

MERLINI, G ;

GAVAZZI, A ;

GRASSO, M ;

DIEGOLI, M ;

FASANI, R ;

BELLOTTI, V ;

MARINONE, G ;

MORBINI, P ;

DALBELLO, B ;

CAMPANA, C ;

FERRANS, VJ .

AMERICAN HEART JOURNAL, 1995, 130 (03) :528-536

[5] Electron and immuno-electron microscopy of abdominal fat identifies and characterizes amyloid fibrils in suspected cardiac amyloidosis [J].

Arbustini, E ;

Verga, L ;

Concardi, M ;

Palladini, G ;

Obici, L ;

Merlini, G .

AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS, 2002, 9 (02) :108-114

[6] The Association of Atrial Tachyarrhythmias with Isolated Atrial Amyloid Disease: Preliminary Observations in Autopsied Heart Specimens [J].

Ariyarajah, Vignendra ;

Steiner, Ivo ;

Hajkova, Petra ;

Khadem, Aliasghar ;

Kvasnicka, Jiri ;

Apiyasawat, Sirin ;

Spodick, David H. .

CARDIOLOGY, 2009, 113 (02) :132-137

[7] Combined heart and liver transplantation for familial amyloidotic polyneuropathy [J].

Arpesella, G ;

Chiappini, B ;

Marinelli, G ;

Mikus, PM ;

Dozza, F ;

Pierangeli, A ;

Magelli, C ;

Salvi, F ;

Leone, O .

JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 2003, 125 (05) :1165-1166

[8] Successful Long-Term Outcome of the First Combined Heart and Kidney Transplant in a Patient with Systemic AL Amyloidosis [J].

Audard, V. ;

Matignon, M. ;

Weiss, L. ;

Remy, P. ;

Pardon, A. ;

Haioun, C. ;

Belhadj, K. ;

Salomon, L. ;

Hillon, M. L. ;

Sahali, D. ;

Vermes, E. ;

Lang, P. ;

Grimbert, P. .

AMERICAN JOURNAL OF TRANSPLANTATION, 2009, 9 (01) :236-240

[9] Biochemical characterisation of amyloid by endomyocardial biopsy [J].

Benson, Merrill D. ;

Breall, Jeffrey ;

Cummings, Oscar W. ;

Liepnieks, Juris J. .

AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS, 2009, 16 (01) :9-14

[10] Amyloid deposits in transthyretin-derived amyloidosis:: cleaved transthyretin is associated with distinct amyloid morphology [J].

Bergström, J ;

Gustavsson, Å ;

Hellman, U ;

Sletten, K ;

Murphy, CL ;

Weiss, DT ;

Solomon, A ;

Olofsson, BO ;

Westermark, P .

JOURNAL OF PATHOLOGY, 2005, 206 (02) :224-232

← 1 2 3 4 5 6 7 8 9 10 →