Immunoglobulin G4-related sclerosing cholangitis

被引:7
作者
Goodchild, George [1 ]
Pereira, Stephen P. [1 ]
Webster, George [1 ]
机构
[1] Univ Coll Hosp, Dept Gastroenterol, 25o Euston Rd, London NW1 2PG, England
关键词
Immunoglobulin G4 related disease; Immunoglobulin G4 cholangiopathy; Autoimmune pancreatitis; Cholangitis sclerosing; Biliary stricture; AUTOIMMUNE PANCREATITIS; IGG4-RELATED DISEASE; G4-ASSOCIATED CHOLANGITIS; HILAR CHOLANGIOCARCINOMA; IGG4-ASSOCIATED CHOLANGITIS; PERORAL CHOLANGIOSCOPY; OBSTRUCTIVE-JAUNDICE; BILIARY STRICTURES; UK COHORT; DIAGNOSIS;
D O I
10.3904/kjim.2018.018
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Immunoglobulin G4-related disease (IgG4-RD) is a systemic fibroinflammatory condition of which IgG4-related sclerosing cholangitis (IgG4-SC) is the biliary manifestation. In this review, we provide an overview of IgG4-RD, with a focus on the biliary manifestations. In particular, we describe the important differential diagnoses of IgG4-SC, namely, primary sclerosing cholangitis and cholangio-carcinoma, outline diagnostic criteria for IgG4-SC, provide insight into possible pathophysiological mechanisms underlying the disease and discuss short and long-term management options of this recently described disease.
引用
收藏
页码:841 / 850
页数:10
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