Frequent immunoglobulin G4 expression in a common variant of primary cutaneous marginal zone B-cell lymphoma

被引：7

作者：

Sun, Jing Ru ^{[1
]}

Nong, Lin ^{[2
]}

Liu, Xiao Qing ^{[1
]}

Tu, Ping ^{[1
]}

Wang, Yang ^{[1
]}

机构：

[1] Peking Univ, Dept Dermatol & Venerol, Hosp 1, 8 Xishiku St, Beijing 100034, Peoples R China

[2] Peking Univ, Dept Pathol, Hosp 1, Beijing, Peoples R China

来源：

AUSTRALASIAN JOURNAL OF DERMATOLOGY | 2018年 / 59卷 / 02期

关键词：

IgG4-related disease; IgG4-related skin disease; Immunohistochemistry; plasma cell; primary cutaneous marginal zone B-cell lymphoma; IGG4-RELATED DISEASE;

D O I：

10.1111/ajd.12699

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Immunoglobulin (Ig)G4 expression was recently observed in a proportion of primary cutaneous marginal zone B-cell lymphoma (PCMZL) with plasmacytic differentiation. IgG4-related disease is characterised by polyclonal lymphoplasmacytic infiltration with IgG4 expression, storiform fibrosis and obliterative phlebitis in histopathology. Here we report three cases of common variants of PCMZL with predominant and varied IgG4 expression, suggesting there is an underlying clonal progression between these two entities.

引用

页码：141 / 145

页数：5

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