Biomarkers of Renal Function: Towards Clinical Actionability

被引：10

作者：

Binnenmars, S. Heleen ^{[1
]}

Hijmans, R. S. ^{[1
]}

Navis, G. ^{[1
]}

de Borst, M. H. ^{[1
]}

机构：

[1] Univ Groningen, Univ Med Ctr Groningen, Dept Internal Med, Div Nephrol, Groningen, Netherlands

来源：

CLINICAL PHARMACOLOGY & THERAPEUTICS | 2017年 / 102卷 / 03期

关键词：

ACUTE KIDNEY INJURY; GELATINASE-ASSOCIATED LIPOCALIN; DIETARY-SODIUM RESTRICTION; GLOMERULAR-FILTRATION-RATE; COLLABORATIVE METAANALYSIS; CYSTATIN-C; URINARY BIOMARKERS; HIGHER ALBUMINURIA; CARDIAC TROPONIN; RISK;

D O I：

10.1002/cpt.765

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

This review provides an overview of the clinical value of themost relevant renal biomarkers, focusing on two main clinical conditions: acute kidney injury and chronic kidney disease. We categorize biomarkers according to their actionability, in terms of a documented response to treatment in relation to outcomes. Furthermore, we introduce a new category of renal biomarkers, metabolic biomarkers, and underscore their capacity to be highly actionable.

引用

页码：481 / 492

页数：12

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