Thermodynamic properties of duplex DNA in microchannel laminar flow

被引:6
|
作者
Yamashita, Kenichi
Miyazaki, Masaya
Yamaguch, Yoshiko
Nakamura, Hiroyuki
Maeda, Hideaki
机构
[1] Natl Inst Adv Ind Sci & Technol, AIST, Nanotechnol Res Inst, Micro & Nano Space Chem Grp, Tosu, Saga 8410052, Japan
[2] Grad Sch Engn Sci, Kasuga, Fukuoka 8168580, Japan
[3] JST, CREST, Tosu, Saga 8410052, Japan
关键词
D O I
10.1002/cphc.200700152
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
Microreactor: Linear dichroism and UV-thermal measurements of duplex DNAs in a continuous-flow microchannel system are presented and the results compared to those from batchwise lab-scale systems. The observed shift in thermal stability is induced by the conformational change under shear stress (see figure). (Graph Presented) © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.
引用
收藏
页码:1307 / 1310
页数:4
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