THE AURORA-A/TPX2 COMPLEX: REGULATION AND ROLES IN TUMORIGENESIS

被引：0
作者：
Asteriti, I. A. [1 ]
Giubettini, M. [1 ]
Rensen, W. M. [1 ]
De Luca, M. [2 ]
Scrofani, J. [1 ]
Lindon, C. [2 ]
Lavia, P. [1 ]
Guarguaglini, G. [1 ]
机构：
[1] Univ Roma La Sapienza, Dept Genet & Mol Biol, CNR, Inst Mol Biol & Pathol, Rome, Italy
[2] Univ Cambridge, Cambridge, England
来源：
CELLULAR ONCOLOGY | 2010年 / 32卷 / 03期
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
引用
收藏
页码：217 / 218
页数：2
相关论文
共 50 条
[1]   The Aurora-A/TPX2 complex: A novel oncogenic holoenzyme? [J].
Asteriti, Italia Anna ;
Rensen, Wilhelmina Maria ;
Lindon, Catherine ;
Lavia, Patrizia ;
Guarguaglini, Giulia .
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER, 2010, 1806 (02) :230-239
[2]   Identification of small molecule inhibitors of the Aurora-A/TPX2 complex [J].
Asteriti, Italia Anna ;
Daidone, Frederick ;
Colotti, Gianni ;
Rinaldo, Serena ;
Lavia, Patrizia ;
Guarguaglini, Giulia ;
Paiardini, Alessandro .
ONCOTARGET, 2017, 8 (19) :32117-32133
[3]   Control of Aurora-A stability through interaction with TPX2 [J].
Giubettini, Maria ;
Asteriti, Italia A. ;
Scrofani, Jacopo ;
De Luca, Maria ;
Lindon, Catherine ;
Lavia, Patrizia ;
Guarguaglini, Giulia .
JOURNAL OF CELL SCIENCE, 2011, 124 (01) :113-122
[4]   Determinants for Aurora-A activation and Aurora-B discrimination by TPX2 [J].
Bayliss, R ;
Sardon, T ;
Ebert, J ;
Lindner, D ;
Vernos, I ;
Conti, E .
CELL CYCLE, 2004, 3 (04) :404-407
[5]   Human TPX2 is required for targeting Aurora-A kinase to the spindle [J].
Kufer, TA ;
Sillje, HHW ;
Koerner, R ;
Gruss, OJ ;
Meraldi, P ;
Nigg, EA .
CELL MOTILITY AND THE CYTOSKELETON, 2003, 54 (02) :179-179
[6]   Human TPX2 is required for targeting Aurora-A kinase to the spindle [J].
Kufer, TA ;
Silljé, HHW ;
Körner, R ;
Gruss, OJ ;
Meraldi, P ;
Nigg, EA .
JOURNAL OF CELL BIOLOGY, 2002, 158 (04) :617-623
[7]   Structural basis of Aurora-A activation by TPX2 at the mitotic spindle [J].
Bayliss, R ;
Sardon, T ;
Vernos, I ;
Conti, E .
MOLECULAR CELL, 2003, 12 (04) :851-862
[8]   Regulation of Xenopus aurora A activation by TPX2 [J].
Eyers, PA ;
Maller, JL .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2004, 279 (10) :9008-9015
[9]   A functional interplay between Aurora-A, Plk1 and TPX2 at spindle poles - Plk1 controls centrosomal localization of Aurora-A and TPX2 spindle association [J].
De Luca, M ;
Lavia, P ;
Guarguaglini, G .
CELL CYCLE, 2006, 5 (03) :296-303
[10]   Mitotic DNA damage targets the Aurora A/TPX2 complex [J].
Bhatia, Payal ;
Menigatti, Mirco ;
Brocard, Michele ;
Morley, Simon ;
Ferrari, Stefano .
CELL CYCLE, 2010, 9 (22) :4592-4599
12345