Reproducibility of resting state spinal cord networks in healthy volunteers at 7 Tesla

被引:52
作者
Barry, Robert L. [1 ,2 ]
Rogers, Baxter P. [1 ,2 ,3 ]
Conrad, Benjamin N. [1 ]
Smith, Seth A. [1 ,2 ,3 ]
Gore, John C. [1 ,2 ,3 ]
机构
[1] Vanderbilt Univ, Inst Imaging Sci, 221 Kirkland Hall, Nashville, TN 37235 USA
[2] Vanderbilt Univ, Med Ctr, Dept Radiol & Radiol Sci, 221 Kirkland Hall, Nashville, TN 37235 USA
[3] Vanderbilt Univ, Dept Biomed Engn, 221 Kirkland Hall, Nashville, TN 37235 USA
关键词
INTRINSIC FUNCTIONAL CONNECTIVITY; FMRI; MRI; RELIABILITY;
D O I
10.1016/j.neuroimage.2016.02.058
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
We recently reported our findings of resting state functional connectivity in the human spinal cord: in a cohort of healthy volunteers we observed robust functional connectivity between left and right ventral (motor) horns and between left and right dorsal (sensory) horns (Barry et al., 2014). Building upon these results, we now quantify the within-subject reproducibility of bilateral motor and sensory networks (intraclass correlation coefficient = 0.54-0.56) and explore the impact of including frequencies up to 0.13 Hz. Our results suggest that frequencies above 0.08 Hz may enhance the detectability of these resting state networks, which would be beneficial for practical studies of spinal cord functional connectivity. (C) 2016 Elsevier Inc. All rights reserved.
引用
收藏
页码:31 / 40
页数:10
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