Relationship of GAD67 regulation to cell cycle and DNA repair in GABA neurons in the adult hippocampus Bipolar disorder versus schizophrenia

被引:13
作者
Benes, Francine M. [1 ,2 ]
机构
[1] McLean Hosp, Program Struct & Mol Neurosci, Belmont, MA 02178 USA
[2] Harvard Univ, Sch Med, Dept Psychiat Neurosci, Boston, MA USA
关键词
GAD(67); cell cycle regulation; DNA repair; neuregulin; HDAC1; PAX5; cyclin D2; GENE-EXPRESSION; CORTEX;
D O I
10.4161/cc.9.4.10820
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
引用
收藏
页码:625 / 627
页数:3
相关论文
共 12 条
[1]   GENE-EXPRESSION FOR GLUTAMIC-ACID DECARBOXYLASE IS REDUCED WITHOUT LOSS OF NEURONS IN PREFRONTAL CORTEX OF SCHIZOPHRENICS [J].
AKBARIAN, S ;
KIM, JJ ;
POTKIN, SG ;
HAGMAN, JO ;
TAFAZZOLI, A ;
BUNNEY, WE ;
JONES, EG .
ARCHIVES OF GENERAL PSYCHIATRY, 1995, 52 (04) :258-266
[2]   Regulation of the GABA cell phenotype in hippocampus of schizophrenics and bipolars [J].
Benes, Francine M. ;
Lim, Benjamin ;
Matzilevich, David ;
Walsh, John P. ;
Subburaju, Sivan ;
Minns, Martin .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2007, 104 (24) :10164-10169
[3]   Site-specific regulation of cell cycle and DNA repair in post-mitotic GABA cells in schizophrenic versus bipolars [J].
Benes, Francine M. ;
Lim, Benjamin ;
Subburaju, Sivan .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2009, 106 (28) :11731-11736
[4]   Circuitry-based gene expression profiles in GABA cells of the trisynaptic pathway in schizophrenics versus bipolars [J].
Benes, Francine M. ;
Lim, Benjamin ;
Matzilevich, David ;
Subburaju, Sivan ;
Walsh, John P. .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2008, 105 (52) :20935-20940
[5]   DNA fragmentation is increased in non-GABAergic neurons in bipolar disorder but not in schizophrenia [J].
Buttner, Ned ;
Bhattacharyya, Sujoy ;
Walsh, John ;
Benes, Francine M. .
SCHIZOPHRENIA RESEARCH, 2007, 93 (1-3) :33-41
[6]  
Costa E, 2007, EPIGENETICS-US, V2, P29
[7]   Signaling to the chromatin during skeletal myogenesis: Novel targets for pharmacological modulation of gene expression [J].
Forcales, SV ;
Puri, PL .
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY, 2005, 16 (4-5) :596-611
[8]   Decrease in reelin and glutamic acid decarboxylase67 (GAD67) expression in schizophrenia and bipolar disorder -: A postmortem brain study [J].
Guidotti, A ;
Auta, J ;
Davis, JM ;
Gerevini, VD ;
Dwivedi, Y ;
Grayson, DR ;
Impagnatiello, F ;
Pandey, G ;
Pesold, C ;
Sharma, R ;
Uzunov, D ;
Costa, E .
ARCHIVES OF GENERAL PSYCHIATRY, 2000, 57 (11) :1061-1069
[9]   Cell cycle regulation in the postmitotic neuron: oxymoron or new biology? [J].
Herrup, Karl ;
Yang, Yan .
NATURE REVIEWS NEUROSCIENCE, 2007, 8 (05) :368-378
[10]   DNA damage and cellular differentiation: More questions than responses [J].
Simonatto, Marta ;
Latella, Lucia ;
Puri, Pier Lorenzo .
JOURNAL OF CELLULAR PHYSIOLOGY, 2007, 213 (03) :642-648