Facile Synthesis of Polysubstituted Oxazoles via A Copper-Catalyzed Tandem Oxidative Cyclization

被引：168

作者：

Wan, Changfeng

Zhang, Jintang

Wang, Sujing

Fan, Jinmin

Wang, Zhiyong ^{[1
]}

机构：

[1] Univ Sci & Technol China, Hefei Natl Lab Phys Sci Microscale, CAS Key Lab Soft Matter Chem, Hefei 230026, Peoples R China

来源：

ORGANIC LETTERS | 2010年 / 12卷 / 10期

关键词：

SP(3) C-H; BOND; DIAZONAMIDE; ACTIVATION; ANNULATION; ARYLATION; ALCOHOLS; PHENOLS; AMIDES; ROUTE;

D O I：

10.1021/ol100688c

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A highly efficient synthesis of polysubstituted oxazoles was developed via a copper-catalyzed tandem oxidative cyclization. The desired products can be obtained from readily available starting materials under mild conditions. This is an attractive alternative method for the synthesis of oxazole derivatives.

引用

页码：2338 / 2341

页数：4

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