Immune function in atherogenesis

被引：71

作者：

Getz, GS ^{[1
]}

机构：

[1] Univ Chicago, Dept Pathol Biochem & Mol Biol, Chicago, IL 60637 USA

来源：

JOURNAL OF LIPID RESEARCH | 2005年 / 46卷 / 01期

关键词：

innate immunity; adaptive immunity; cytokines;

D O I：

10.1194/jlr.R400013-JLR200

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In this overview to a new thematic series on the immune system and atherogenesis, I provide a very brief summary of current conceptions of atherogenesis, of the innate and adaptive immune systems, and of the participation of the latter in atherogenesis, with particular emphasis on studies of the involvement of the immune system in atherosclerosis reported in the last 2 years. This is followed by a short outline of the eight reviews that will make up this thematic series. The overview is concluded with some caveats that should be considered in the analysis of atherosclerosis in experimental animals.

引用

页码：1 / 10

页数：10

共 62 条

[1] Innate and acquired immunity in atherogenesis [J].

Binder, CJ ;

Chang, MK ;

Shaw, PX ;

Miller, YI ;

Hartvigsen, K ;

Dewan, A ;

Witztum, JL .

NATURE MEDICINE, 2002, 8 (11) :1218-1226

[2] IL-5 links adaptive and natural immunity specific for epitopes of oxidized LDL and protects from atherosclerosis [J].

Binder, CJ ;

Hartvigsen, K ;

Chang, MK ;

Miller, M ;

Broide, D ;

Palinski, W ;

Curtiss, LK ;

Corr, M ;

Witztum, JL .

JOURNAL OF CLINICAL INVESTIGATION, 2004, 114 (03) :427-437

[3] Reduced atherosclerosis in MyD88-null mice links elevated serum cholesterol levels to activation of innate immunity signaling pathways [J].

Björkbacka, H ;

Kunjathoor, VV ;

Moore, KJ ;

Koehn, S ;

Ordija, CM ;

Lee, MA ;

Means, T ;

Halmen, K ;

Luster, AD ;

Golenbock, DT ;

Freeman, MW .

NATURE MEDICINE, 2004, 10 (04) :416-421

[4] Tumor necrosis factor receptor and ligand superfamily family members TNFRSF14 and LIGHT - New players in human atherogenesis [J].

Bobik, A ;

Kalinina, N .

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2001, 21 (12) :1873-1875

[5] Co-stimulation and plaque-antigen-specific T-cell responses in atherosclerosis [J].

Buono, C ;

Lichtman, AH .

TRENDS IN CARDIOVASCULAR MEDICINE, 2004, 14 (04) :166-172

[6] B7-1/B7-2 costimulation regulates plaque antigen-specific T-cell responses and atherogenesis in low-density lipoprotein receptor-deficient mice [J].

Buono, C ;

Pang, H ;

Uchida, Y ;

Libby, P ;

Sharpe, AH ;

Lichtman, AH .

CIRCULATION, 2004, 109 (16) :2009-2015

[7] Influence of interferon-γ on the extent and phenotype of diet-induced atherosclerosis in the LDLR-deficient mouse [J].

Buono, C ;

Come, CE ;

Stavrakis, G ;

Maguire, GF ;

Connelly, PW ;

Lichtman, AH .

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2003, 23 (03) :454-460

[8] Influence of C3 deficiency on atherosclerosis [J].

Buono, C ;

Come, CE ;

Witztum, JL ;

Maguire, GF ;

Connelly, PW ;

Carroll, M ;

Lichtman, AH .

CIRCULATION, 2002, 105 (25) :3025-3031

[9] Protective immunity against atherosclerosis carried by B cells of hypercholesterolemic mice [J].

Caligiuri, G ;

Nicoletti, A ;

Poirier, B ;

Hansson, GK .

JOURNAL OF CLINICAL INVESTIGATION, 2002, 109 (06) :745-753

[10] γδ T cells:: Functional plasticity and heterogeneity [J].

Carding, SR ;

Egan, PJ .

NATURE REVIEWS IMMUNOLOGY, 2002, 2 (05) :336-345

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