Troponins in myocardial infarction and injury

被引:13
作者
Potter, Julia M. [1 ]
Hickman, Peter E. [1 ,2 ]
Cullen, Louise [3 ]
机构
[1] Australian Natl Univ, Med Sch, Canberra, ACT, Australia
[2] Canberra Hosp, Canberra, ACT, Australia
[3] Royal Brisbane & Womens Hosp, Emergency & Trauma Ctr, Brisbane, Qld, Australia
关键词
acute coronary syndromes; myocardial infarction; cardiac troponins; point-of-care testing; HIGH-SENSITIVITY TROPONIN; CARDIAC TROPONIN;
D O I
10.18773/austprescr.2022.006
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Troponins are proteins that are integral components of the contractile mechanism of muscle, including cardiac muscle. Cardiac troponins I and T can be detected in the blood of most people after puberty, at concentrations reflecting cardiac mass, sex and age. Current laboratory assays are approximately 1000 times more sensitive than those used previously. They also have higher sensitivity than point-of-care assays. The measurement of cardiac troponins is used primarily to assist in the diagnosis or exclusion of myocardial injury. Serial tests in acute coronary syndrome are guided by the Universal Definition of Myocardial Infarction.
引用
收藏
页码:53 / 57
页数:5
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