Current Neoadjuvant Strategies in Rectal Cancer

被引：38

作者：

Julien, Lucas A. ^{[1
]}

Thorson, Alan G. ^{[1
,2
,3
]}

机构：

[1] Colon & Rectal Surg Inc, Omaha, NE USA

[2] Univ Nebraska, Omaha, NE 68182 USA

[3] Creighton Univ, Omaha, NE 68178 USA

来源：

JOURNAL OF SURGICAL ONCOLOGY | 2010年 / 101卷 / 04期

关键词：

rectal cancer; neoadjuvant therapy; chemotherapy; radiation therapy; review; SYNCHRONOUS LIVER METASTASES; PREOPERATIVE CHEMORADIATION; COLORECTAL-CARCINOMA; MESORECTAL EXCISION; IMPROVED SURVIVAL; COMPLETE RESPONSE; RESECTION; RADIOTHERAPY; CHEMOTHERAPY; SURGERY;

D O I：

10.1002/jso.21480

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Treatment modalities in rectal cancer have undergone a slow, evolutionary transition over the past 30 years. More recently, contemporary descriptions of advanced preoperative chemotherapy and radiation schema have led to a rapid revolution in the management of this disease. In this review we focus on current evidence-based neoadjuvant strategies used in the treatment of locally advanced rectal cancer and metastatic rectal disease. Finally, we provide a foundation for discussion of still unresolved issues. J Surg. Oncol. 2010;101:321-326. (C) 2010 Wiley-Liss, Inc.

引用

页码：321 / 326

页数：6

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