Probable DRESS syndrome induced by IL-1 inhibitors

被引：3

作者：

Polivka, L. ^{[1
,2
,3
]}

Diana, J. S. ^{[1
,2
,3
]}

Soria, A. ^{[4
,5
]}

Bodemer, C. ^{[1
,2
,6
]}

Quartier, P. ^{[1
,2
,3
]}

Fraitag, S. ^{[1
,2
,7
]}

Bader-Meunier, B. ^{[1
,2
,3
]}

机构：

[1] Paris Descartes Sorbonne Paris Cite Univ, Paris, France

[2] IMAGINE Inst, Paris, France

[3] Necker Enfants Malad Hosp, AP HP, Dept Pediat Hematol Immunol & Rheumatol, 149 Rue Sevres, F-75015 Paris, France

[4] UPMC Univ Paris 06, Sorbonne Univ, Immunol & Infect Dis Ctr Paris Cimi Paris, INSERM,U1135, Paris, France

[5] Tenon Hosp, AP HP, Dept Dermatol & Allergol, Paris, France

[6] Necker Enfants Malad Hosp, AP HP, Dept Dermatol, Paris, France

[7] Necker Enfants Malad Hosp, AP HP, Dept Pathol, Paris, France

来源：

ORPHANET JOURNAL OF RARE DISEASES | 2017年 / 12卷

关键词：

DRESS; IL-1; inhibitors; Autoinflammatory disease; SYSTEMIC SYMPTOMS DRESS; DRUG REACTION; EOSINOPHILIA;

D O I：

10.1186/s13023-017-0645-x

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Interleukin (IL)-1 inhibitors have been increasingly used for treating autoinflammatory diseases during the last 10 years, but the spectrum of their possible side effects is not yet fully known. Here, we bring physicians' attention to a new severe complication of IL-1 inhibitors, manifesting as a probable drug reaction with eosinophilia and systemic symptoms (DRESS) in two patients.

引用

页数：3

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