Defect formation induced by PAMAM dendrimers on Pt-supported bilayer lipid membranes investigated by electrochemistry

被引：17
作者：
Huang, WM [1 ]
Han, XJ [1 ]
Wang, EK [1 ]
机构：
[1] Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Electroanalyt Chem, Changchun 130022, Jilin, Peoples R China
来源：
JOURNAL OF THE ELECTROCHEMICAL SOCIETY | 2003年 / 150卷 / 04期
关键词：
D O I：
10.1149/1.1554920
中图分类号：
O646 [电化学、电解、磁化学];
学科分类号：
081704 ;
摘要：
The interaction of polyamidoamine (PAMAM) dendrimers (generations 1-7) with supported bilayer lipid membranes was studied by cyclic votammetry and ac impedance. It is shown that the dendrimers (generations 4-6) can induce defects in the Pt-electrode-supported bilayer lipid membrane. The ability of dendrimers to induce defects was dependent on their shapes and surface charge. The results are consistent with a change in the morphology of the dendrimers from an open, branched structure for generations 1-4 to a closed, increasingly compact surface for generations 5-7. (C) 2003 The Electrochemical Society.
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页码：E218 / E221
页数：4
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